Dolutegravir and the management of HIV/AIDS in the South African adult population

N Hurbans, P Naidoo - SA Pharmaceutical Journal, 2024 - journals.co.za
… 96 weeks in HIV-1 infected antiretroviral naïve adult subjects … The NAMSAL trial in Cameroon
did not demonstrate superior … , the low incidence of reported resistance may restrict the …

[PDF][PDF] Integrase Strand Transfer Inhibitor–Based Regimens

B RAL - clinicalinfo.hiv.gov
… is available and shows no INSTI-resistance mutations (AIII). In … noninferiority trial conducted
in Cameroon, compared DTG to … The incidence of resistance with DTG is much lower than …

[HTML][HTML] Impact of antiretroviral therapy on lipid metabolism of human immunodeficiency virus-infected patients: Old and new drugs

J da Cunha, LMF Maselli, ACB Stern… - World journal of …, 2015 - ncbi.nlm.nih.gov
… longer quality of life for HIV-1-infected patients. Apart from the … ][9] and integrase strand
transfer inhibitors (InSTIs)[10] (Table ​… , HIV-infected individuals exhibit a higher prevalence of …

Weight changes with integrase strand transfer inhibitor therapy in the management of HIV infection: a systematic review

EK Hester, S Greenlee… - Annals of …, 2022 - journals.sagepub.com
… if they were case reports, pregnant patients, pediatric patients, or did not measure weight or
… The incidence of obesity was also not significantly different between DTG compared to EFV (…

[HTML][HTML] Technologies for HIV-1 drug resistance testing: inventory and needs

KJ Metzner - Current Opinion in HIV and AIDS, 2022 - journals.lww.com
… The prevalence of HIV DR is stable or even declining in … potential mutations related to drug
resistance outside the target … DBS have been used successfully in samples from Cameroon [7…

Simplification to dual therapy containing lamivudine and raltegravir or dolutegravir in HIV-infected patients on virologically suppressive antiretroviral therapy

L Calza, V Colangeli, M Borderi, D Testi… - Journal of …, 2020 - academic.oup.com
… , except for a higher incidence of headache and sleeping … in both antiretroviral-naive and
-experienced patients, and has … cohort analysis of HIV-1-infected adult patients referred to our …

… in insulin sensitivity and serum leptin concentration after the switch from a ritonavir-boosted PI to raltegravir or dolutegravir in non-diabetic HIV-infected patients

L Calza, V Colangeli, M Borderi… - Journal of …, 2019 - academic.oup.com
… A prospective cohort analysis of HIV-1-infected adult patients … study conducted in Cameroon,
insulin resistance (defined by … HIV-infected, antiretroviral-naive adults were randomized to …

[HTML][HTML] Evaluation of HIV-1 integrase variability by combining computational and probabilistic approaches

D Vergni, D Santoni, Y Bouba, S Lemme… - Infection, Genetics and …, 2022 - Elsevier
… events occurring in treated and untreated HIV-1 infected individuals. The reliability of the …
across all three domains of integrase was conserved (≤1% mutation prevalence), regardless of …

Risk of Emergent Dolutegravir Resistance Mutations In People Living With HIV: A Rapid Scoping Review

C Chu, K Tao, V Kouamou, A Avalos, J Scott, PM Grant… - medRxiv, 2024 - medrxiv.org
… adds The prevalence of virological failure with the development of HIV mutations associated
… testing; INSTI – integrase strand transfer inhibitor; NRTIs – nucleoside/nucleotide reverse …

HIV MDR is still a relevant issue despite its dramatic drop over the years

D Armenia, D Di Carlo, P Flandre… - Journal of …, 2020 - academic.oup.com
… the prevalence of resistance among isolates from HIV-1-infected ART-experienced patients
over … Trend of prevalence of major resistance mutations for PIs, NRTIs and NNRTIs over the …