Mitochondrial quality control as a therapeutic target

HB Suliman, CA Piantadosi - Pharmacological reviews, 2016 - ASPET
… They participate in cell communication and regulation of inflammation and are important
considerations in aging, drug toxicity, and pathogenesis. The cell’s capacity to maintain its …

[PDF][PDF] Unique challenges in the development of therapies for neurological disorders

G O'Neill - Clinical Trials in Neurology: Design, Conduct …, 2012 - ndl.ethernet.edu.et
… development should be a high priority. For timely delivery of … termination codons in Duchenne
muscular dystrophy and A β … with intractable epilepsy. Epilepsia 2006; 47: 681–94. 19. …

[PDF][PDF] Pignol et al.(43) Pub. Date: Jun. 11, 2009

PFR Lassauniere - researchgate.net
effect on the cells vis-a-vis cell death. [0027] In the case of the treatment of muscular dystrophy,
the invention … and Washed With 50 ml of Water and 50 ml of salt Water. After drying over …

3-Oxopiperazinium derivatives as agonists of nerve growth factor and their use as medicaments

B Moreno, P Villoslada, J Messeguer… - 2011 - digital.csic.es
… This invention applies to the area of therapeutics for … (seizures). Also preferably, the uses
and methods of the present … with Lewy bodies, spinal muscular atrophy; nerve inflammation, …

Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity

IN Pessah, G Cherednichenko, PJ Lein - Pharmacology & therapeutics, 2010 - Elsevier
… Of these various adverse health effects, developmental neurotoxicity has emerged as a
particularly vulnerable endpoint in PCB toxicity. Arguably the most pervasive biological effects of …

3-oxopiperazinium derivatives as agonists of nerve growth factor receptors and their use as medicaments

B Moreno, P Villoslada, J Messeguer, G Navarro… - 2011 - digital.csic.es
… Field of invention This invention applies to the area of … , pathological neuronal burst (seizures).
Also preferably, the … with Lewy bodies, spinal muscular atrophy; nerve inflammation, such …

Emerging Roles of Non-Coding RNA in Neuronal Function and Dysfunction

SG Fagan, S Pfeiffer - COVID-19, Neuroimmunology and Neural …, 2021 - books.google.com
… The discovery and functional analysis of an increasing number … lobe epilepsy patients,
and in animal models of epilepsy … for the treatment of spinal muscular atrophy. Phase II and III …

US FDA approved drugs from 2015–June 2020: a perspective

P Bhutani, G Joshi, N Raja, N Bachhav… - Journal of Medicinal …, 2021 - ACS Publications
… leading to their discoveries have been emphasized. Finally, … for the treatment of partial-onset
seizures. For the treatment of … the treatment of Duchenne muscular dystrophy. Cerliponase …

BASIC KNOWLEDGE EMBRYOLOGY AND DEVELOPMENT

R McWilliam, I Horrocks - Practical Paediatric Problems: A …, 2005 - books.google.com
… 1 per 3500 male births Duchenne muscular dystrophy (DMD) is … q The first priority after a
child has had a febrile seizure is to … epilepsy–they are both the result of disordered ion channel

Cardiomyopathy in children: classification and diagnosis: a scientific statement from the American Heart Association

SE Lipshultz, YM Law, A Asante-Korang, ED Austin… - Circulation, 2019 - Am Heart Assoc
… will help shape the future research priorities in this set of … such as Duchenne and Becker
muscular dystrophies, Barth … like episodes), MERFF (myoclonic epilepsy with ragged red fibers), …