CSCs in breast cancerone size does not fit all: Therapeutic advances in targeting heterogeneous epithelial and mesenchymal CSCs

A Sulaiman, S McGarry, X Han, S Liu, L Wang - Cancers, 2019 - mdpi.com
… for ER (Estrogen Receptor), PR (Progesterone Receptor), and … , Wnt/β-catenin mutations
commonly found in other cancer … Increased NF-κB signaling in CD4+ T cells has been linked

Signaling pathways and natural compounds in triple-negative breast cancer cell line

C Dewi, A Fristiohady, R Amalia, NK Khairul Ikram… - Molecules, 2022 - mdpi.com
… some signaling pathways, such as Wnt/β-Catenin [19], NF-κB [… of progesterone receptor (PR),
estrogen receptor (ER), and … and erlotinib, are used to block the EGFR signaling pathway in …

Cancer and pregnancy: parallels in growth, invasion, and immune modulation and implications for cancer therapeutic agents

SG Holtan, DJ Creedon, P Haluska… - Mayo Clinic …, 2009 - Elsevier
… of EVT cells, inhibition of the Wntβ-catenin pathway can block … to form diploid,
cisplatin-resistant escape cells. In … /T H 2 polarization is effected through the activation of NF-κB

Targeting the hedgehog pathway in MET mutation cancers and its effects on cells associated with cancer development

Y Du, H Sun, Z Shi, X Sui, B Liu, Z Zheng, Y Liu… - Cell Communication and …, 2023 - Springer
… of HGF in CAFs in an NF-κB-dependent manner and modify … signaling pathways such as
IL-6/STAT3 and Wnt/β-catenin [… of the cross-talk between the primary c-MET and Hh pathways

Targeted drug therapy to overcome chemoresistance in triple-negative breast cancer

M Kumari, PT Krishnamurthy… - Current cancer drug …, 2020 - ingentaconnect.com
… the NF-κB pathway plays an essential role in cancer initiation … Altered activation of Wnt/β-catenin
signaling in BCSCs was … crosstalk between these pathways has conferred resistance to …

Signaling mechanisms of chemoresistance in breast cancer stem cells for therapeutics

S Shivhare, A Das - Cancer Stem Cells and Signaling Pathways, 2024 - Elsevier
… Overexpression of Nectin-4 upregulates the Wnt/β-catenin … Recruitment of NF-κB, and Notch1
to the promoter of the … paradigms that lead to chemoresistance against erlotinib. Blocking …

[PDF][PDF] The WNT/ROR Pathway in Cancer: From Signaling to Therapeutic Intervention. Cells 2021, 10, 142

K Menck, S Heinrichs, C Baden, A Bleckmann - 2021 - pdfs.semanticscholar.org
… The WNT/β-catenin pathway is the best characterized WNT … light-chain-enhancer of activated
B cells (NF-κB), phosphoinositide 3-… Taken together, its crosstalk with these two pathways is …

Targeting estrogens and various estrogen-related receptors against Non-Small Cell Lung Cancers: a perspective

R Maitra, P Malik, TK Mukherjee - Cancers, 2021 - mdpi.com
… wherein estrogen receptor-AP-1 cross-talk was demonstrated … cells via suppressed IKK-β/NF-κB
signaling pathways [57]. … treated with erlotinib and fulvestrant rather than erlotinib alone. …

Targeting stem cells in the realm of drug-resistant breast cancer

P Dey, M Rathod, A De - Breast Cancer: Targets and Therapy, 2019 - Taylor & Francis
… Citation93 Gefitinib or erlotinib, prescribed to BC patients with … inflammatory cascade via
NF-κB pathway leading to chronic … , TGF-β, and Wnt/β-catenin pathways are also being used in …

An update on the molecular biology of glioblastoma, with clinical implications and progress in its treatment

E Verdugo, I Puerto, MÁ Medina - Cancer Communications, 2022 - Wiley Online Library
… is modulated by cell-to-cell crosstalk within the tumor … process regulated by TNF-α/NF-κB
signaling or ASCL1. To sum up… decreased expression of the Wnt/β-catenin pathway. This result …