An analysis of the multifaceted roles of heme in the pathogenesis of cancer and related diseases

T Wang, A Ashrafi, P Modareszadeh, AR Deese… - Cancers, 2021 - mdpi.com
… -1 and heme, which is crucial for nerve-cancer cell cross-talk. … by p50 NF-κB–CSF-R1–C3aR
axis. This promotes more HO-… cell chemoresistance to anti-cancer reagents erlotinib and …

Therapeutic potential of targeting the SUMO pathway in cancer

A Kukkula, VK Ojala, LM Mendez, L Sistonen… - Cancers, 2021 - mdpi.com
… The SUMO pathway undergoes constant cross talk with other post-translational … NF-κB
essential modifier (NEMO) [113]. Furthermore, SUMOylation regulates activation of Wnt/β-catenin

Signal transduction pathways in breast cancer–drug targets and challenges

S Azab, A Al-Hendy - … , cell growth and signalling pathways …, 2011 - books.google.com
… to be extensive crosstalk between the pathways driving … The NF-κB pathway is triggered in
response to microbial and … agents targeting the EGFR, Wnt/β-catenin and/or Notch cascades …

RNA based approaches to profile oncogenic pathways from low quantity samples to drive precision oncology strategies

A Van De Stolpe, W Verhaegh, JY Blay, CX Ma… - Frontiers in …, 2021 - frontiersin.org
… in HCC827 cell lines treated with DMSO (gray), erlotinib (yellow… (through crosstalk between
pathways) in the PI3K pathway. … one signaling pathway may lead to activation of a resistance-…

Flavonoids for the treatment of breast cancer, present status and future prospective

S Sahoo, P Mohapatra… - … Cancer Agents in Medicinal …, 2023 - ingentaconnect.com
… signaling pathways (STAT3 signaling, Wnt/β-catenin pathway… the VEGF signaling pathway,
inhibition of NF-κB and mTOR … cells, endothelial cells etc.) that crosstalk with the tumor cells

[HTML][HTML] RAIDS atlas of significant genetic and protein biomarkers in cervical cancer

S Scholl, DB Roufai, LL Chérif… - Journal of Gynecologic …, 2023 - ncbi.nlm.nih.gov
… It displays crosstalk with many oncogenic signaling pathways … T cells, GITR signaling is
mediated by activation of NF-κB … in CC cells by modulating EMT via Wnt/β-catenin signaling [ 49 ]. …

[图书][B] Identification of a resistance mechanism to IGF-IR targeting in triple negative breast cancer cells

J Tsui - 2017 - search.proquest.com
… binding protein (CREB) and NF-κB to upregulate the expression of … β (TGFβ), and Wnt/β-catenin
signaling. The MSL is distinct … To our knowledge, no direct crosstalk between IGF-IR and …

Identification of the biomarkers and pathological process of heterotopic ossification: weighted gene co-expression network analysis

S Wang, J Tian, J Wang, S Liu, L Ke, C Shang… - Frontiers in …, 2020 - frontiersin.org
… ), progesterone receptor membrane component 1 (PGRMC1), … Due to the development of
genetic testing technology in … research showed pulmonary adenocarcinoma cells around the …

[HTML][HTML] Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways

D Hiss - Journal of oncology, 2012 - hindawi.com
… lines, a recent study showed that activation of the NF-κB pathway … survival pathways in
cancers through crosstalk with VEGF, HIF-1, … The Wnt/β-catenin signaling pathway should not be …

[图书][B] Combating resistance to epidermal growth factor receptor inhibitors in triple negative breast cancer

JM Madden - 2014 - search.proquest.com
… and provides a potential pathway crosstalk that is important … (used in this dissertation work),
erlotinib, AZD9291, and CLO-… promoter), procaspase-9, NF-ΚB (nuclear factor kappa-light-…