The Role of Notch-1-Mediated Repression of PTEN on Growth and Cancer Stem Cell Survival in Trastuzumab Resistant, Her2+ Breast Cancer

AT Baker - 2017 - search.proquest.com
… Mechanisms of crosstalk between the HER family of RTKs and … pathways including the:
Wnt/β-catenin (Ayyanan et al., 2006), TNFa/IKK/NF-κB (Cao et al., 2007), and Notch pathways (…

Retrospective analysis of yap/TAZ/MST/lats gene expressions in ınvasive ductal carcinoma breast cancer patients

M Sabour Takanlou - acikbilim.yok.gov.tr
… reduces p53 phosphorylation and increases its association with the p52 NF-κB subunit. …
Crosstalk Hippo Pathway with Wnt The Hippo pathway regulates Wnt/β- Catenin pathway

[HTML][HTML] Cancer (Cell) Biology

K Bednarek, M Kostrzewska-Poczekaj, M Szaumkessel… - gsn.io.gliwice.pl
… 1450 related to the wnt/β-catenin signaling pathway. Next we … of NF-κB pathway in the
human lung adenocarcionoma … on interactions and crosstalk between different pathways. Here, …

[HTML][HTML] Unraveling Biomarker Signatures in Triple-Negative Breast Cancer: A Systematic Review for Targeted Approaches

P Pastena, H Perera, A Martinino, W Kartsonis… - International Journal of …, 2024 - mdpi.com
… with the EGFR inhibitor Erlotinib showed additional benefits, … Wnt Pathway and the nuclear
factor-kappa B (NF-κB) pathwayWnt/β-catenin genes in TNBC cells. The direct link between …

Patient-derived organoids as a model for tumor research

J Wang, X Feng, Z Li, Y Chen, W Huang - Progress in Molecular Biology …, 2022 - Elsevier
… to interrogate drug sensitivity, cellular crosstalk, invasion, … the activation of the Wnt/β-catenin
pathway by the addition of … (inhibiting TNF-α-mediated NF-κB stimulation). However, the …

[HTML][HTML] Modulation of Notch Signaling by Small-Molecular Compounds and Its Potential in Anticancer Studies

A Czerwonka, J Kałafut, M Nees - Cancers, 2023 - mdpi.com
… AKT, mTOR, NF-κB [22], or HIF-1α [23], ultimately leading to … considering the cross-talk
with other signaling pathways, such … In addition to the Wnt/β-catenin, Hedgehog, PI3K/Akt/mTOR, …

[图书][B] Mechanisms of action of non-steroidal anti-inflammatory drugs (NSAIDs) in colon cancer

SS Pathi - 2012 - search.proquest.com
… this receptor can engage in autocrine signaling and crosstalk … The major components of
Wnt/β-catenin pathway is the β-… induces drug resistance due to increased binding NF-κB with …

Effective Targeting of Epithelial Mesenchymal Transition-Driven Breast Cancer Stem Cells Using Ophiobolin A, A Natural Product

K Reisenauer - 2021 - search.proquest.com
… , including NF-κB-promoted Jagged-1 expression and AP-1-… in a single pathway, rather it is
the outcome of cross-talk between … pathway, Wnt/β-catenin, Hedgehog, and Notch pathways.…

[图书][B] Molecular Profiling of Chemotherapy Acquired Resistance in Triple Negative Breast Cancer Cell Lines

E Ahmadzadeh - 2015 - search.proquest.com
pathways including EGF, MET, and Wnt/β-catenin pathways. In … ) by inducing the translocation
of NF-ΚB (Nuclear Factor-… up to 20 fold, suggesting a cross talk between the drug-binding …

[HTML][HTML] Emergence of nanotechnology as a powerful cavalry against triple-negative breast cancer (TNBC)

A Chaudhuri, DN Kumar, D Dehari, S Singh, P Kumar… - Pharmaceuticals, 2022 - mdpi.com
… (nerve growth factor), and Wnt/β-catenin pathways. It was thus … A phase II clinical trial of
Gefitinib and Erlotinib combination … by down-regulation of NF-κB in cells, promoting apoptosis […