[HTML][HTML] Mechanisms of action of natural products on type 2 diabetes

T Wang, YY Wang, MY Shi, L Liu - World Journal of Diabetes, 2023 - ncbi.nlm.nih.gov
… exhibiting resistance to the toxicity of cobalt chloride[42,43]. … of pancreatic β cells, and
exerts its antiapoptotic effect on STZ-… These results indicated that propolis increased the serum …

Molecular mechanistic pathways targeted by natural antioxidants in the prevention and treatment of chronic kidney disease

M Mohany, MM Ahmed, SS Al-Rejaie - Antioxidants, 2021 - mdpi.com
… Chrysin derived from bee propolis reduced kidney fibrosis … of honeybee propolis that has
been shown to protect against lithium-… GSPE also protected the kidneys in STZ-induced diabetic …

Exploration of natural flavones' bioactivity and bioavailability in chronic inflammation induced-type-2 diabetes mellitus

L Miao, C Liu, MS Cheong, R Zhong, Y Tan… - Critical Reviews in …, 2023 - Taylor & Francis
… Eventually, insulin secretion caused by the destruction of pancreatic β cells will be reduced,
… that ethanolic propolis containing chrysin exhibited anti-diabetic bioactivity in STZ-induced …

[HTML][HTML] An investigation into the potential action of polyphenols against human Islet Amyloid Polypeptide aggregation in type 2 diabetes

A Mahboob, DKL Senevirathne, P Paul, F Nabi… - International Journal of …, 2023 - Elsevier
… and dysfunction in pancreatic β-cells. In healthy individuals, β-cells produce insulin which is
a … In individuals with T2D, the β-cells are either dysfunctional or their mass is reduced, thus …

Phytochemicals in the Management of Diabetes

Q Abbas, SM Al-Thawadi, S Perna - 2022 - books.rsc.org
… plants, honey, and propolis (Scheme 5.16). … in STZ-induced diabetic rats when it was given
orally. It exerted its effect via reducing lipid peroxidation and protecting the pancreatic β-cells. …

The emerging role of redox-sensitive Nrf2–Keap1 pathway in diabetes

E Bhakkiyalakshmi, D Sireesh, P Rajaguru… - Pharmacological …, 2015 - Elsevier
protect pancreatic β-cells as well as peripheral nerves against damage induced by IL-1β,
IFN-γ and streptozotocin (… the progression of renal injury in STZ-induced diabetic rats and has …

Anonna muricata L.(soursop) seed oil improves type 1 diabetes parameters in vivo and in vitro

LC Pinto, AT Cerqueira-Lima, S dos Santos Suzarth… - PharmaNutrition, 2018 - Elsevier
… muricata seed oil (AmSO) in streptozotocin (STZ)-induced in … β cells (RIN-m5F) exposed
to STZ were either treated or not … /kg weight of the ethanol extract of propolis, for 30 days and …

Antihyperglycemic and antioxidant effects of a flavanone, naringenin, in streptozotocin–nicotinamide-induced experimental diabetic rats

T Annadurai, AR Muralidharan, T Joseph… - Journal of physiology …, 2012 - Springer
… Hence, in the present study, STZ–nicotinamide-induced … protected the pancreatic islets
from free radical-mediated oxidative stress and preserved the integrity of pancreatic β-cells, …

Evaluation of antidiabetic antihyperlipidemic and pancreatic regeneration, potential of aerial parts of Clitoria ternatea

PR Verma, PR Itankar, SK Arora - Revista Brasileira de Farmacognosia, 2013 - Elsevier
… were further evaluated for pancreatic β-cells regeneration activity … of streptozotocin (STZ) in
a single dose of 45 mg/kg body weight. … Estimation of total flavonoid content in propolis by two …

Streptozotocin-induced diabetes in rats: effects of White Butterfly (Clerodendrum volubile) leaves on blood glucose levels, lipid profile and antioxidant status

OR Molehin, OI Oloyede… - … mechanisms and methods, 2018 - Taylor & Francis
… level, lipid profile and antioxidant status in streptozotocin (STZ)-induced diabetes in rats, in
… in stimulating insulin secretion from remnant β-cells of the pancreas, which further enhances …