[HTML][HTML] An investigation into the potential action of polyphenols against human Islet Amyloid Polypeptide aggregation in type 2 diabetes

A Mahboob, DKL Senevirathne, P Paul, F Nabi… - International Journal of …, 2023 - Elsevier
… and dysfunction in pancreatic β-cells. In healthy individuals, β-cells produce insulin which is
a … In individuals with T2D, the β-cells are either dysfunctional or their mass is reduced, thus …

Phytochemicals in the Management of Diabetes

Q Abbas, SM Al-Thawadi, S Perna - 2022 - books.rsc.org
… plants, honey, and propolis (Scheme 5.16). … in STZ-induced diabetic rats when it was given
orally. It exerted its effect via reducing lipid peroxidation and protecting the pancreatic β-cells. …

Antihyperglycemic and antioxidant effects of a flavanone, naringenin, in streptozotocin–nicotinamide-induced experimental diabetic rats

T Annadurai, AR Muralidharan, T Joseph… - Journal of physiology …, 2012 - Springer
… Hence, in the present study, STZ–nicotinamide-induced … protected the pancreatic islets
from free radical-mediated oxidative stress and preserved the integrity of pancreatic β-cells, …

Galangin controls streptozotocin-caused glucose homeostasis and reverses glycolytic and gluconeogenic enzyme changes in rats

AA Aloud, V Chinnadurai… - … of Physiology and …, 2020 - Taylor & Francis
… with streptozotocin (STZ). Glibenclamide is a standard synthetic drug which is used to control
hyperglycaemia by arousing insulin secretion from β-cells. … STZ is a toxic chemical that has …

The emerging role of redox-sensitive Nrf2–Keap1 pathway in diabetes

E Bhakkiyalakshmi, D Sireesh, P Rajaguru… - Pharmacological …, 2015 - Elsevier
protect pancreatic β-cells as well as peripheral nerves against damage induced by IL-1β,
IFN-γ and streptozotocin (… the progression of renal injury in STZ-induced diabetic rats and has …

Evaluation of antidiabetic antihyperlipidemic and pancreatic regeneration, potential of aerial parts of Clitoria ternatea

PR Verma, PR Itankar, SK Arora - Revista Brasileira de Farmacognosia, 2013 - Elsevier
… were further evaluated for pancreatic β-cells regeneration activity … of streptozotocin (STZ) in
a single dose of 45 mg/kg body weight. … Estimation of total flavonoid content in propolis by two …

Anonna muricata L.(soursop) seed oil improves type 1 diabetes parameters in vivo and in vitro

LC Pinto, AT Cerqueira-Lima, S dos Santos Suzarth… - PharmaNutrition, 2018 - Elsevier
… muricata seed oil (AmSO) in streptozotocin (STZ)-induced in … β cells (RIN-m5F) exposed
to STZ were either treated or not … /kg weight of the ethanol extract of propolis, for 30 days and …

Streptozotocin-induced diabetes in rats: effects of White Butterfly (Clerodendrum volubile) leaves on blood glucose levels, lipid profile and antioxidant status

OR Molehin, OI Oloyede… - … mechanisms and methods, 2018 - Taylor & Francis
… level, lipid profile and antioxidant status in streptozotocin (STZ)-induced diabetes in rats, in
… in stimulating insulin secretion from remnant β-cells of the pancreas, which further enhances …

[HTML][HTML] Galangin attenuates diabetic cardiomyopathy through modulating oxidative stress, inflammation and apoptosis in rats

MH Abukhalil, OY Althunibat, SH Aladaileh… - Biomedicine & …, 2021 - Elsevier
Streptozotocin (STZ)- induced type 1 diabetes in rodents has … /kg did not induce any toxic
effects in healthy rats and showed … ROS generation in pancreatic β-cells, STZ also causes DNA …

Ursolic acid regulates gut microbiota and corrects the imbalance of Th17/Treg cells in T1DM rats

W Chen, Y Yu, Y Liu, CJ Song, HH Chen, C Tang… - PLoS …, 2022 - journals.plos.org
… progressive destruction of pancreatic β-cells, and modulate … Other evidence from
animal experiments implies that propolis … , as it protects islet cells from streptozotocin (STZ)-induced …