Some possible interactions between gliclazide and nebivolol in experimentally induced diabetic hypertensive albino rats

NHF El-Baroudy, F Fayed, A Sekinah… - Zagazig University …, 2013 - journals.ekb.eg
… of reactive oxygen species through its antioxidant effect(9). Also, gliclazide can improve
endothelial dysfunction and this effect is likely related ,also, to its antioxidant effect (10). …

Restoring the dysfunctional endothelium

E Osto, G Coppolino, M Volpe… - Current pharmaceutical …, 2007 - ingentaconnect.com
… spontaneously hypertensive rats with endothelial dysfunctionblood pressure, suggesting an
independent protective action … An improvement of endothelial function by nebivolol has also …

Nebivolol: An Endothelium-Friendly Selective β: 1:-Adrenoceptor Blocker

Y Gao, PM Vanhoutte - Journal of Cardiovascular Pharmacology, 2012 - journals.lww.com
hypertensive patients, nebivolol but not atenolol decreased the plasma concentration of
ADMA, and this was accompanied by an improvement in endothelial functionprotective effects

Vasodilating β-adrenoceptor blockers as cardiovascular therapeutics

N Toda - Pharmacology & therapeutics, 2003 - Elsevier
… In healthy volunteers and hypertensive patients, infused ia nebivolol increased forearm …
endothelial dysfunction in spontaneously hypertensive rats is prevented by the antioxidant action

Endothelial dysfunction in the hypertensive state: mechanisms of hypertensive cardiovascular complications

AB Reiss, AK Nath, B Nath… - Current Hypertension …, 2008 - ingentaconnect.com
… may reverse hypertension-associated endothelial dysfunction. … target for therapeutic
intervention in essential hypertension. … Use of nebivolol for the treatment of endothelial dysfunction

Nebivolol: the somewhat-different β-adrenergic receptor blocker

T Münzel, T Gori - Journal of the American College of Cardiology, 2009 - jacc.org
… processes underlying endothelial dysfunction in cardiovascular … , nebivolol has been shown
to have protective effects in … treatment on hypertensive patients, the use of nebivolol actually …

Nebivolol prevents vascular NOS III uncoupling in experimental hyperlipidemia and inhibits NADPH oxidase activity in inflammatory cells

H Mollnau, E Schulz, A Daiber, S Baldus… - … , and vascular biology, 2003 - Am Heart Assoc
… β receptor blockade with nebivolol may improve endothelial function in hyperlipidemia and
effects on endothelial function in hypertensive patients may therefore indicate that nebivolol

Nebivolol: more than a highly selective Beta blocker

Y Karter - Recent Patents on Cardiovascular Drug Discovery …, 2007 - ingentaconnect.com
reversed by administration of excess L-arginine [2, 16-18]. … whereas nebivolol favourably
acts on endothelial function and … , nebivolol and atenolol significantly reduced blood pressure

Nephroprotective effects of nebivolol in 2K1C rats through regulation of the kidney ROS-ADMA-NO pathway

Y Wang, M Niu, S Yin, F Zhang, R Shi - Pharmacological Reports, 2018 - Springer
… the protective effect of nebivolol against kidney damage and … study were: 1) nebivolol
reversed both kidney injurys, … 5 restores endothelial function in enovascular hypertension. J …

Effect of nebivolol and atenolol on brachial artery flow-mediated vasodilation in patients with coronary artery disease

JP Lekakis, A Protogerou, C Papamichael… - … drugs and therapy, 2005 - Springer
… to examine the effects of nebivolol on endothelial function in the … for its endothelium-protective
effects since this action con… Additionally, in hypertensive patients free of CAD, nebivolol