Endothelial dysfunction and hypertension

D Konukoglu, H Uzun - Hypertension: from basic research to clinical …, 2017 - Springer
… approach for hypertension. This chapter reviews the roles of endothelial dysfunction in
hypertension by … Some β-blockers have endothelial protective effects. It can improve the …

Protection against oxidative stress in diabetic rats: role of angiotensin AT1 receptor and beta 1-adrenoceptor antagonism

M Dorenkamp, A Riad, S Stiehl, F Spillmann… - European journal of …, 2005 - Elsevier
… To elucidate pathways mediating protective effects, the … development of diabetes-induced
endothelial dysfunction. Both … differing modes of action (eg β 1 -selective agents like nebivolol, …

Effects of β-blockers on glucose and lipid metabolism

VA Fonseca - Current medical research and opinion, 2010 - Taylor & Francis
… to improve endothelial function among patients with hypertension and diabetes or ischemic
… In another small study in patients with newly diagnosed stage 1 hypertension, nebivolol, but …

Endothelial dysfunction and its clinical implications

P Poredos, AV Poredos, I Gregoric - Angiology, 2021 - journals.sagepub.com
Endothelial dysfunction observed in hypertension appears to … Nebivolol induces NO
production via activation of β-3 … of lipid-lowering effects, but their protective effects on EF are most …

Reversal of subclinical left ventricular dysfunction by antihypertensive treatment: a prospective trial of nebivolol against metoprolol

D Vinereanu, C Gherghinescu, AO Ciobanu… - … of hypertension, 2011 - journals.lww.com
… Thus, nebivolol might have better protective effects on left ventricular function than … that,
in patients with hypertension and type 2 diabetes, endothelial dysfunction induces subclinical …

Pharmacological prevention of eNOS uncoupling

H Li, U Forstermann - Current pharmaceutical design, 2014 - ingentaconnect.com
… The protective effects of nebivolol are likely to be attributable … with diabetes [117] and to
improve endothelial function of the … endothelial dysfunction in spontaneously hypertensive rats. J …

Endothelial dysfunction in conduit arteries and in microcirculation. Novel therapeutic approaches

D Tousoulis, C Simopoulou, N Papageorgiou… - Pharmacology & …, 2014 - Elsevier
… of endothelial dysfunction to atherogenesis and review the methods that assess endothelial
function … A blood pressure cuff is also placed on one arm (study arm), whereas the other is …

Nebivolol ameliorates cisplatin‐induced nephrotoxicity in rats

MA Morsy, GH Heeba - Basic & clinical pharmacology & …, 2016 - Wiley Online Library
… whether nebivolol possesses a protective effect against … mechanisms underlying this
potential effect. Nephrotoxicity was … endothelial cells from pulmonary arterial hypertension lungs …

Effects of treatment strategy on endothelial function

L Tomasoni, S Sitia, C Borghi, AFG Cicero… - Autoimmunity …, 2010 - Elsevier
… of both arterial hypertension and endothelial dysfunction, and … β-blockers (carvedilol,
nebivolol, labetalol) have now been … can control or reverse endothelial dysfunction and oxidative …

The central role of endothelial dysfunction in cardiorenal syndrome

J Zhang, T Bottiglieri, PA McCullough - Cardiorenal medicine, 2017 - karger.com
… information about the different pathogeneses of ED in hypertensive and diabetic subjects. …
, Ritter JM: The vasodilator action of nebivolol in forearm vasculature of subjects with essential …