Non-recommended dosing of direct oral anticoagulants in the treatment of acute pulmonary embolism is related to an increased rate of adverse events

R Chopard, G Serzian, S Humbert, N Falvo… - Journal of Thrombosis …, 2018 - Springer
… , and chronic thromboembolic pulmonary hypertension (CTEPH). … an initial dose of rivaroxaban,
four were directly treated with the … opportunity for multidisciplinary quality improvement to …

Long-term clinical course of acute pulmonary embolism

PL Den Exter, T Van der Hulle, M Lankeit, MV Huisman… - Blood reviews, 2013 - Elsevier
after cessation of anticoagulant therapy. These adverse events include recurrent venous
thromboembolism, chronic thromboembolic pulmonary hypertension, … and decreased quality of …

To screen or not to screen for chronic thromboembolic pulmonary hypertension after acute pulmonary embolism

YM Ende-Verhaar, MV Huisman, FA Klok - Thrombosis research, 2017 - Elsevier
… is associated with a very poor prognosis and high risk of … outpatient clinic after an initial
anticoagulant treatment period of … patients with CTEPH have a substantially reduced quality of life …

Multicentre observational screening survey for the detection of CTEPH following pulmonary embolism

N Coquoz, D Weilenmann, D Stolz… - European respiratory …, 2018 - Eur Respiratory Soc
… to the haemodynamics and quality of life [5–7]. Therefore, … matching the initial 1699 patients
with pulmonary embolism with … 3 months of effective anticoagulation therapy and radiological …

Diagnosis of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism

FA Klok, F Couturaud, M Delcroix… - European Respiratory …, 2020 - Eur Respiratory Soc
… /or decreased quality of life following an acute PE diagnosis), … received 3 months of
anticoagulation therapy, mild COPD … signs of CTEPH on initial CTPA scans with confirmed acute

Safety and efficacy of direct oral anticoagulants in patients with chronic thromboembolic pulmonary hypertension

I Benzidia, C Robitaille, A Abualsaud, L McDonald… - Thrombosis …, 2023 - Elsevier
pulmonary emboli cause chronic obstruction of the … with CTEPH are treated with DOAC
from the time of their initial … -term survival, severe functional limitations and poor quality of life […

An update on the management of acute high-risk pulmonary embolism

R Chopard, J Behr, C Vidoni, F Ecarnot… - Journal of Clinical …, 2022 - mdpi.com
initial bolus dose followed by a continuous infusion. A shift to LMWH or direct oral anticoagulant
(DOAC) was allowed early after … Early recognition of underlying CTEPH in acute PE is of …

Long-term treatment of venous thromboembolism

C Kearon, SR Kahn - Blood, The Journal of the American …, 2020 - ashpublications.org
… chronic thromboembolic pulmonary hypertension (CTEPH), … that the risks and benefits of
indefinite anticoagulant therapy are … quality of life and is costly, its prevention and treatment are …

Acute pulmonary embolism: a review

Y Freund, F Cohen-Aubart, B Bloom - Jama, 2022 - jamanetwork.com
… , 0 (indicates low risk with a risk of 1.5% recurrent venous thromboembolism and a 1.1% …
regarding the diagnosis and treatment of acute pulmonary thromboembolism in adults. …

Short-and long-term mortality risk after acute pulmonary embolism

R Gupta, DD Fortman, DR Morgenstern… - Current cardiology …, 2018 - Springer
… of stay, quality of life, and possibly mortality risk reduction. Long-… therapy with tenecteplase
plus heparin anticoagulation … The incidence of CTEPH after an initial PE ranges from 1 to 4% …