Quaternized chitosan-coated nanofibrous implants loaded with gossypol prepared by electrospinning and their efficacy against Graffi myeloid tumor

M Ignatova, K Kalinov, N Manolova… - Journal of …, 2014 - Taylor & Francis
… mats displayed in vitro high antiproliferative activity against HeLa tumor cells. To the best of
… -tumor activity of nanofibrous implants prepared thereof against solid Graffi myeloid tumor

Quaternized chitosan-coated nanofibrous materials containing gossypol: Preparation by electrospinning, characterization and antiproliferative activity towards HeLa …

M Ignatova, N Manolova, R Toshkova, I Rashkov… - International journal of …, 2012 - Elsevier
Nanofibrous polylactide-based materials loaded with a natural polyphenolic … Implants
prepared thereof exhibit good antitumor activity in vitro and in vivo towards myeloid Graffi tumor, as …

Drug-loaded electrospun materials in wound-dressing applications and in local cancer treatment

М Ignatova, I Rashkov, N Manolova - Expert opinion on drug …, 2013 - Taylor & Francis
… The chitosan-coated PLA and PLA/PEG mats inhibited the … The anticancer efficacy of these
nanofibrous implants was … gallate, gossypol (GOS) in nanofibrous materials intended for local …

Advances in electrospinning of nanofibers and their biomedical applications

HT Sasmazel, O Ozkan - Current Tissue Engineering, 2013 - ingentaconnect.com
Quaternized chitosancoated nanofibrous materials containing gossypol: Preparation by
electrospinning, … Antitumor activity of quaternized chitosan-based electrospun implants against …

Antiproliferative activity of nanofibers containing quaternized chitosan and/or doxorubicin against MCF-7 human breast carcinoma cell line by apoptosis

M Ignatova, L Yossifova, E Gardeva… - Journal of bioactive …, 2011 - journals.sagepub.com
… We found that nanofibrous implants containing QCh, coPLA, … a solid myeloid tumor, initially
induced by the Graffi virus. While … -loaded QCh-containing nanofibrous electrospun materials …

Pharmaceutical applications of electrospinning

S Nangare, N Jadhav, P Ghagare, T Muthane - Annales pharmaceutiques …, 2020 - Elsevier
… These QCh- and DOX-based implants were found to exhibit high cytotoxicity against Graffi
nanofibrous polylactide-based mats loaded with a natural polyphenolic compound gossypol (…

Chitosan-modified nanocarriers as carriers for anticancer drug delivery: Promises and hurdles

FS Alhodieb, MA Barkat, HA Barkat, H Ab Hadi… - International Journal of …, 2022 - Elsevier
quaternized CS implants which exhibited higher inhibitory (two fold) activity towards graffi
tumor cells as compared to the gossypol … The chitosan coated MNPs could not clot the blood …

Electrospun-based systems in cancer therapy

M Norouzi, B Nazari, DW Miller - Electrospun materials for tissue …, 2017 - Elsevier
loading capacity and high encapsulation efficiency. In addition, high interconnected porosity
of electrospun nanofibrous-… were fabricated and implanted to cover the solid tumors in mice. …

Recent advances in electrospun for drug delivery purpose

M Liu, Y Zhang, S Sun, AR Khan, J Ji… - Journal of drug …, 2019 - Taylor & Francis
… In recent years, drug-loaded electrospun nanofibers have … [Citation27] found that PVA
nanofiber patch used for the … CS has been reported to combat Graffi myeloid tumours and HeLa …

Poly (3-hydroxybutyrate)/caffeic acid electrospun fibrous materials coated with polyelectrolyte complex and their antibacterial activity and in vitro antitumor effect …

MG Ignatova, NE Manolova, IB Rashkov… - Materials Science and …, 2016 - Elsevier
… has emerged as a very suitable technique for the preparation of drug-loaded nanofibrous
effect of quaternized chitosan-coated nanofibrous mats containing gossypol demonstrated in …