Synapsin regulation of vesicle organization and functional pools
M Bykhovskaia - Seminars in cell & developmental biology, 2011 - Elsevier
… (brown) vesicle pools at hippocampal synapses are intermixed within a cluster… deletion
significantly reduced exocytosis, but not the density of docked vesicles at synapses lacking Rab3a…
significantly reduced exocytosis, but not the density of docked vesicles at synapses lacking Rab3a…
Membrane traffic in the secretory pathway: Regulation of secretory vesicle traffic by Rab small GTPases
M Fukuda - Cellular and Molecular Life Sciences, 2008 - Springer
… (but see [47]; Rab3A deletion reduced vesicle docking at the … of the mouse stomach, and
deletion of Slp2-a reduces both … , a greatly reduced number of synaptic vesicles docked to the …
deletion of Slp2-a reduces both … , a greatly reduced number of synaptic vesicles docked to the …
Synapsin II and Rab3a cooperate in the regulation of epileptic and synaptic activity in the CA1 region of the hippocampus
P Feliciano, R Andrade… - Journal of Neuroscience, 2013 - Soc Neuroscience
… Here, we show that Rab3a gene deletion rescues the overexcitable phenotype … )
Rab3a-mediated vesicle recruitment regulates short-term plasticity at the mouse diaphragm synapse. …
Rab3a-mediated vesicle recruitment regulates short-term plasticity at the mouse diaphragm synapse. …
Rab3 superprimes synaptic vesicles for release: implications for short-term synaptic plasticity
OM Schlüter, J Basu, TC Südhof… - Journal of …, 2006 - Soc Neuroscience
… release indicate that Rab3 acts on a subset of primed, fusion … of vesicular release probability,
we used quadruple Rab3A, … was not caused by the removal of Rab3a alone, because we …
we used quadruple Rab3A, … was not caused by the removal of Rab3a alone, because we …
[PDF][PDF] RIM determines Ca2+ channel density and vesicle docking at the presynaptic active zone
… conditional removal of RIM proteins leads to a strong decrease of … functions that ensure fast
rates of transmitter release at synapses. … Single Rab3A KO mice exhibit a deficit in the activity-…
rates of transmitter release at synapses. … Single Rab3A KO mice exhibit a deficit in the activity-…
[HTML][HTML] Synapsin I accelerates kinetics of neurotransmitter release in mouse motor terminals
WL Coleman, M Bykhovskaia - Synapse (New York, NY), 2009 - ncbi.nlm.nih.gov
… The diaphragms of adult mice were dissected and synaptic … release kinetics was unaffected
by synapsin gene deletion. … last stages of synaptic vesicle fusion and demonstrates that …
by synapsin gene deletion. … last stages of synaptic vesicle fusion and demonstrates that …
Molecular insights into the roles of rab proteins in intracellular dynamics and neurodegenerative diseases
… ’ state is triggered by addition or deletion of a phosphate group (… They are key players in
neurotransmitter release. SV … with Rab3A and Rabphilin for synaptic vesicle docking and fusion. …
neurotransmitter release. SV … with Rab3A and Rabphilin for synaptic vesicle docking and fusion. …
Redundant functions of RIM1α and RIM2α in Ca2+‐triggered neurotransmitter release
… , exocytosis of transmitter‐filled synaptic vesicles at the … on the diaphragm in a discrete
spatially restricted endplate … and 2α deletion on synapse structure and neurotransmitter release. …
spatially restricted endplate … and 2α deletion on synapse structure and neurotransmitter release. …
Synaptic assembly of the brain in the absence of neurotransmitter secretion
M Verhage, AS Maia, JJ Plomp, AB Brussaard… - Science, 2000 - science.org
… Deletion of a single protein, Munc18-1, in mice leads to a complete loss of neurotransmitter
secretion from synaptic vesicles … , earlier developing synapse, we investigated the diaphragm …
secretion from synaptic vesicles … , earlier developing synapse, we investigated the diaphragm …
Impaired activity-dependent plasticity of quantal amplitude at the neuromuscular junction of Rab3A deletion and Rab3A earlybird mutant mice
X Wang, Q Wang, S Yang, M Bucan… - Journal of …, 2011 - Soc Neuroscience
… Rab3A is a small GTPase associated with synaptic vesicles … of vesicles that fuse through
an effect on docking, vesicle … reduced (R 2 = 0.09 and 0.12, respectively). In addition, four …
an effect on docking, vesicle … reduced (R 2 = 0.09 and 0.12, respectively). In addition, four …