[PDF][PDF] The role of regulated secretion in neurite outgrowth, synapse formation and neuronal survival: Munc-18-1 as a spider in the web

JH Heeroma - 2005 - research.vu.nl
… Although SNAREs are believed to be essential for vesicle fusion, synaptic vesicle fusion is
not … RIM binds to munc13 and interacts with rab3A. Deletion of RIM1α does not have a strong …

Advances in neurobiology of the neuromuscular junction: implications for the anesthesiologist

M Naguib, P Flood, JJ McArdle… - The Journal of the …, 2002 - pubs.asahq.org
Synapse maturation involves the formation of a motor nerve terminal with densely packed
synaptic vesicles containing the transmitter … nonsynaptic membrane, synaptic nAChRs become …

Calmodulin enhances ribbon replenishment and shapes filtering of synaptic transmission by cone photoreceptors

MJ Van Hook, CM Parmelee, M Chen… - Journal of General …, 2014 - rupress.org
… single vesicle fusion events, we found that individual vesicles … However, deletion of Munc13
in photoreceptors had no effect … sites rather than vesicles makes Rab3a an unlikely mediator …

Functions of the APP gene family in the nervous system: insights from mouse models

D Aydin, SW Weyer, UC Müller - Experimental brain research, 2012 - Springer
Diaphragm preparations from newborn APP/APLP2-DKO … nucleotides in the cytoplasmic
tail were deleted, which led to a … , for synapse formation, transmitter release, synaptic plasticity …

Protein–protein interactions and protein modules in the control of neurotransmitter release

F Benfenati, F Onofri, S Giovedi - … Transactions of the …, 1999 - royalsocietypublishing.org
… Both synaptic vesicle tra¤cking and neurotransmitter release … Thus, if a vesicle component
is responsible for the removal of … protein rab3A regulates a late step in synaptic vesicle fusion. …

Structure and function of tetanus and botulinum neurotoxins

C Montecucco, G Schiavo - Quarterly reviews of biophysics, 1995 - cambridge.org
decrease the number of vesicles capable of fusion and … This protein cannot be deleted or
altered under the selective … small synaptic vesicles or other vesicles whose recycling is linked to …

C-terminal ECFP fusion impairs synaptotagmin 1 function: crowding out synaptotagmin 1

W Han, JS Rhee, A Maximov, W Lin… - Journal of Biological …, 2005 - ASBMB
… type background alters synaptic neurotransmitter release ( … Rab3A (Cl42.2, 1:1000) and
Alexa 568-conjugated goat-anti-mouse IgG (1:1000, Molecular Probes), while the diaphragm

Homeostatic plasticity of the mammalian neuromuscular junction

KL Engisch, X Wang, MM Rich - Vertebrate Motoneurons, 2022 - Springer
… of neurotransmitter released via fusion of synaptic vesicles … in mice with a point mutation in
the synaptic vesicle protein … the presynaptic terminal, altering Rab3A function, which triggers …

The synaptic proteome

M Laßek, J Weingarten, W Volknandt - Cell and tissue research, 2015 - Springer
… proteins with their targets, and the effect of their deletion opens … of docked synaptic vesicles
include synaptotagmin-1, rab3a, … and APLP2-dKO mice showed that synaptic vesicle density, …

[PDF][PDF] Trans-synaptic homeostasis at the myasthenic neuromuscular junction

JJ Plomp - Front Biosci (Landmark Ed), 2017 - article.imrpress.com
… rats reduced the average MEPP amplitude in diaphragm NMJs … from Drosophila NMJ studies
is Rab3A-interacting molecule (… Postsynaptic deletion of dystrophin in Drosophila causes …