Effects of Sex Steroid Hormones on Sertoli Cells Metabolic Pathways

ACD Martins - 2012 - search.proquest.com
… cultures of immature rat SCs treated with 17β-estradiol (E2) or -dihydrotestosterone (DHT). …
proliferation and apoptosis in adult male rat adipose tissue." J Nutr 138(11): 2156-2163. …

DHT and E2 as modulators of apoptotic signaling in rat Sertoli cells

VLS Simões - 2012 - search.proquest.com
17β-estradiol (E2) and dihydrotestosterone (DHT) on the apoptotic signaling pathways in
immature rat Sertoli cells … role on the regulation of mitochondria related pro-apoptotic factors. …

Molecular Mechanisms Elicited by d-Aspartate in Leydig Cells and Spermatogonia

MM Di Fiore, A Santillo, S Falvo, S Longobardi… - International Journal of …, 2016 - mdpi.com
… has been detected in Leydig cells, Sertoli cells and germ cells, notably in spermatogonia, …
is converted into -dihydrotestosterone by 5α-reductase (SRD5A1), or into 17β-estradiol by …

The expression of inducible nitric oxide synthase (iNOS) in the testis and epididymis of rats with a dihydrotestosterone (DHT) deficiency

A Kolasa, M Marchlewicz, R Kurzawa… - Cellular and Molecular …, 2009 - degruyter.com
… action of testosterone and -dihydrotestosterone during … , CY Regulation of Sertoli cell tight
junction dynamics in the rat testis via … /protein kinase G signaling pathway: an in vitro study. …

[HTML][HTML] Estrogenic regulation of testicular expression of stem cell factor and c-kit: implications in germ cell survival and male fertility

S Correia, MR Alves, JE Cavaco, PF Oliveira… - Fertility and sterility, 2014 - Elsevier
… thus to male infertility because increased levels of 17β-estradiol (E 2 ) have been detected
… on isolated Sertoli cells that showed that 100 nM of E 2 diminishes Sertoli cells apoptosis by …

Physiology of Testicular Function

J Wistuba, N Neuhaus, E Nieschlag - Andrology: Male Reproductive …, 2023 - Springer
… by immature, not yet terminally differentiated Sertoli cells and … Sertoli cells, the apoptosis of
spermatocytes, spermatids and … converted into 17β-estradiol and -dihydrotestosterone (DHT…

Glucose transport and metabolism in sertoli cell: relevance for male fertility

TR Dias, AD Martins, VP Reis… - Current Chemical …, 2013 - ingentaconnect.com
… , namely -dihydrotestosterone (DHT) and 17β-estradiol (E2): as … Regulation of Apoptotic
Signaling Pathways by … /protein kinase B signaling in immature rat Sertoli cells. Endocrinology …

Sexual Steroid Regulation of Spermatogenesis: New Actors Enter the Stage

SFTS Laurentino - 2011 - search.proquest.com
… testosterone and -dihydrotestosterone) to the regulation of … importance of estrogens (like
17β-estradiol), has also been … Sertoli cells were first described by Enrico Sertoli in 1865 as …

… xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells

BT Akingbemi, CM Sottas, AI Koulova… - …, 2004 - academic.oup.com
… mimic the action of the natural hormone 17β-estradiol (E 2 ) in … In the rat, prepubertal Sertoli
cells are a source of estrogen, … ER, and the estrogen signaling pathway regulates adipocyte …

Dihydrotestosterone as a protective agent in chronic experimental autoimmune encephalomyelitis

S Giatti, R Rigolio, S Romano, N Mitro, B Viviani… - …, 2015 - karger.com
… Alternatively, T can be aromatized into 17β-estradiol, a … EAE rats compared to controls,
suggesting that apoptosis may also … antiapoptotic effects of DHT observed in Sertoli cells [69,70]. …