Short and long-term motor and behavioral effects of diazoxide and dimethyl sulfoxide administration in the mouse after traumatic brain injury

CS Budinich, LB Tucker, D Lowe… - Pharmacology …, 2013 - Elsevier
Traumatic brain injury (TBI) is a worldwide phenomenon that affects all ages and socioeconomic
classes and results in varying degrees of immediate and delayed motor, cognitive, and …

Remote ischemic conditioning

G Heusch, HE Bøtker, K Przyklenk, A Redington… - Journal of the American …, 2015 - jacc.org
… (80), limb RIPC in rats not only reduced infarct size, but also preserved connexin-43 …
animal models, the extent of platelet activation is related to the extent of subsequent tissue injury

The role of acid sphingomyelinase inhibition in repetitive mild traumatic brain injury

GM Niziolek, RS Hoehn, AP Seitz, PL Jernigan… - Journal of Surgical …, 2021 - Elsevier
… inhibition would preserve neuronal regeneration and decrease … murine model of repetitive
mild traumatic brain injury (rmTBI). Our … inflammation, cognitive and motor impairment, and a …

Microglia/macrophage polarization dynamics in white matter after traumatic brain injury

G Wang, J Zhang, X Hu, L Zhang… - Journal of Cerebral …, 2013 - journals.sagepub.com
murine model of controlled cortical impact (CCI). Based on our previous observations in
ischemic injury models, … long-term deficiencies in motor and cognitive functions in TBI patients, …

[HTML][HTML] Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions

A Jarrahi, M Braun, M Ahluwalia, RV Gupta, M Wilson… - Biomedicines, 2020 - mdpi.com
… Further, U83836E also showed the ability to preserve … the cerebral damage, and improved
cognition and motor ability [… resolution in a murine model of intracerebral hemorrhage (ICH) …

Neuroprotective Effect of Sub-lethal Hyperthermia Preconditioning in a Rat Model of Repeated Closed Head Injury

J Xiong, Y Lv, X Ma, G Peng, C Wu, J Hou, Y Zhang… - Neuroscience, 2023 - Elsevier
… ideal animal model to induces cumulative neuronal injury, neurological dysfunction, and
cognitive … This finding suggests that SHP preserves the surviving neurons. Additionally, MBP, a …

[HTML][HTML] Surgery, neuroinflammation and cognitive impairment

A Alam, Z Hana, Z Jin, KC Suen, D Ma - EBioMedicine, 2018 - thelancet.com
… In addition, evidence supporting novel therapeutic avenues, such as nicotinic and HMGB-1
targeting and remote ischaemic pre-conditioning, is limited and necessitates further …

[HTML][HTML] Timing is everything: Exercise therapy and remote ischemic conditioning for acute ischemic stroke patients

H Lee, HJ Yun, Y Ding - Brain circulation, 2021 - journals.lww.com
… functions[ 11 12 ] and motor skills.[ 13 ] Clinical trials have … Various injuries to the head,
such as traumatic brain injury,[ … that vascular recanalization helps to preserve the function of …

Remote ischemic post-conditioning improves neurological function by AQP4 down-regulation in astrocytes

S Li, X Hu, M Zhang, F Zhou, N Lin, Q Xia… - Behavioural brain …, 2015 - Elsevier
… attenuate cerebral damage after transient middle cerebral … lethal consequence of traumatic
brain injury was cellular edema, … The RIPC preserved the cerebral ischemia and suppressed …

Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model

LE Goldstein, AM Fisher, CA Tagge, XL Zhang… - Science translational …, 2012 - science.org
Traumatic brain injury (TBI) is the “signature” injury of the conflicts in Afghanistan and
Iraq and is associated with psychiatric symptoms and long-term cognitive disability. Recent …