Biochemical hazards during three phases of assisted reproductive technology: repercussions associated with epigenesis and imprinting

Y Menezo, K Elder, P Clement, A Clement… - International journal of …, 2022 - mdpi.com
… In this paper, the key role of methylation processes in epigenesis, namely the essential …
present in human, bovine, and mouse oocytes [20]. Methionine adenosyl transferase (MAT) …

Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease

L Barbier-Torres, B Murray, JW Yang, J Wang… - Nature …, 2022 - nature.com
2a). To see if MATα1 could be a PIN1 target we first … c Area under the curve of the
phosphorylated peptide which … the importance of MATα1-PIN1 interaction in ALD, we inhibited it by …

[PDF][PDF] Tasks of some dietary essential nutrients on epigenetics and one carbon metabolism in livestock during production

MS Yusuf, AK El-Sayed, AH Amr, Z Sun, H Cui - academia.edu
… In this review, our team will focus on the role of important … followed by G) dinucleotide (Regions
of the genome rich in CpG … of CpG within these regions is generally associated with gene …

[HTML][HTML] … supplementation to heifers for the first 14 d of the estrous cycle alters the plasma and hepatic one-carbon metabolite pool and methionine-folate cycle enzyme …

MS Crouse, HC Freetly… - Journal of Animal …, 2023 - academic.oup.com
… of the roles of one-carbon metabolites in beef cattle is “insufficient”… and products in each
cycle and their connected pathways. … Methionine adenosyl transferase 2A is one of the enzymes …

Chromatin capture links the metabolic enzyme AHCY to stem cell proliferation

S Aranda, A Alcaine-Colet, E Blanco, E Borràs… - Science …, 2019 - science.org
… an unexpected chromatin function for adenosylhomocysteinase, a … 2A). The AHCY substrate
SAH is the product of the S-… Mouse preimplantation embryos cultured in the presence of 3-…

Methionine is a metabolic dependency of tumor-initiating cells

Z Wang, LY Yip, JHJ Lee, Z Wu, HY Chew… - Nature medicine, 2019 - nature.com
… In the first step, methionine adenosyltransferase II alpha (… 2a) 33,34 . Following this protocol,
we immediately assessed … of TIC function, and we highlight methionine cycle inhibition as a …

The Guinea Pig: A New Model for Human Preimplantation Development

JR Canizo, C Zhao, S Petropoulos - bioRxiv, 2024 - biorxiv.org
… a potentially 311 conserved role of methionine in the morula … expression related to the timing
of developmental milestones … human, mouse, rat, and bovine, we also observe that not 648 …

[HTML][HTML] Nutritional status impacts epigenetic regulation in early embryo development: a scoping review

S Cai, S Quan, G Yang, M Chen, Q Ye, G Wang… - Advances in …, 2021 - Elsevier
its sequence is highly conserved, it plays different roles in … This result suggests that
during the preimplantation gene … (Bhmt),methionine adenosyltransferase 2B (Mat2b), and …

Bovine blastocyst development depends on threonine catabolism

V Najafzadeh, H Henderson, R Martinus, B Oback - bioRxiv, 2018 - biorxiv.org
… of methionine adenosyltransferases that catalyse the conversion of … the role of threonine
and methionine in bovine blastocyst … 2A). The gene was detected in blastocysts where …

Associations of the Single Bovine Embryo Growth Media Metabolome with Successful Pregnancy

E Tsopp, K Kilk, E Taalberg, P Pärn, A Viljaste-Seera… - Metabolites, 2024 - mdpi.com
growth media groups were related to lipids. The multifaceted … In conclusion, our study affirms
the significance of lipid beta-… processes in blastocyst preimplantation development. When …