Roles of TRPV1 and Neuropeptidergic Receptors in Dorsal Root Reflex-Mediated Neurogenic Inflammation Induced by Intradermal Injection of Capsaicin

Q Lin, D Li, X Xu, X Zou, L Fang - Molecular Pain, 2007 - journals.sagepub.com
… However, no direct evidence demonstrates that the release … , bicuculline, reduced dramatically
the capsaicin-induced … 1 receptors by capsazepine, blockade of CGRP receptors did not …

Capsaicin inhibits the in vitro binding of peptides selective for μ-and κ-opioid, and nociceptin-receptors

M Wollemann, E Ioja, S Benyhe - Brain research bulletin, 2008 - Elsevier
antinociception was substantially diminished after capsaicin … , evidence has accumulated
for the existence of a capsaicinreceptors the TRPV1 selective antagonist capsazepine was …

[PDF][PDF] The role of spinal cord vanilloid (TRPV1) receptors in pain modulation

D Špicarová, J Paleček - Physiol. Res, 2008 - researchgate.net
Capsaicin induced increase of sIPSCs frequency was … This effect was abolished by TRPV1
antagonist capsazepine … X, LARSON AA: An antinociceptive effect of capsaicin in the adult …

A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain …

P Honore, CT Wismer, J Mikusa, CZ Zhu… - … of Pharmacology and …, 2005 - ASPET
… injection of capsazepine effectively blocked capsaicin-induced … , provide further evidence
that TRPV1 receptor activation … the antinociceptive profile for selective TRPV1 antagonists. …

Effects of TRPV1 receptor antagonists on stimulated iCGRP release from isolated skin of rats and TRPV1 mutant mice

G Pethö, I Izydorczyk, PW Reeh - Pain, 2004 - journals.lww.com
… abolished, respectively, capsaicin-induced iCGRP release while I-… that capsazepine and
I-RTX not only compete with capsaicin … : evidence for a spinal receptor site in capsaicin-induced

[HTML][HTML] Activation of TRPV1 by capsaicin induces functional Kinin B1 receptor in rat spinal cord microglia

S Talbot, JP Dias, K Lahjouji, MR Bogo… - Journal of …, 2012 - Springer
… and pro-inflammatory cytokines in capsaicin-induced B 1 R … two generations of TRPV1
antagonists (capsazepine and SB-… ), they caused antinociceptive effects in capsaicin-treated rats (…

[HTML][HTML] Use of capsaicin to treat pain: mechanistic and therapeutic considerations

MK Chung, JN Campbell - Pharmaceuticals, 2016 - mdpi.com
… prevented by capsazepine [95] or a specific antagonist of … P and capsaicin-induced anti-nociception
is unclear [103]. In … The prevailing evidence suggests that capsaicin-induced

Vanilloid receptors: new insights enhance potential as a therapeutic target

A Szallasi, PM Blumberg - Pain, 1996 - Elsevier
evidence that the vanilloid receptor is not a single receptor … oxygen uptake recognizes
capsaicin and capsazepine with high … Heterogeneity of capsaicin-induced currents in cultured rat …

[PDF][PDF] Inhibition by capsazepine of resiniferatoxin-and capsaicin-induced contractions of guinea pig trachea.

JL Ellis, BJ Undem - Journal of Pharmacology and Experimental …, 1994 - Citeseer
… RTX was about 20-fold more potent than capsaicin, with-log (M) ECro … capsaicin receptor
antagonist capsazepine(1 0 M) effectively inhibited responses to both RTX and capsaicin in a …

[HTML][HTML] Evidence of TRPV1 receptor and PKC signaling pathway in the antinociceptive effect of amyrin octanoate

R Marcon, AP Luiz, MF de Paula Werner, CS Freitas… - Brain research, 2009 - Elsevier
… , like capsazepine, a selective capsaicin receptor antagonist, … and central antinociceptive
effects against capsaicin-inducedreceptor expression in dorsal root ganglion and spinal cord …