Semitelechelic HPMA copolymers functionalized with triphenylphosphonium as drug carriers for membrane transduction and mitochondrial localization
J Callahan, J Kopeček - Biomacromolecules, 2006 - ACS Publications
… Mitochondria-targeting drug carriers could be used as effective vectors for anticancer drugs,
as well as other drugs, … , or other signal transduction factors localized in the mitochondria. …
as well as other drugs, … , or other signal transduction factors localized in the mitochondria. …
Novel HPMA copolymer-bound constructs for combined tumor and mitochondrial targeting
V Cuchelkar, P Kopečková… - Molecular …, 2008 - ACS Publications
… using triphenylphosphonium (TPP) ions as mitochondrial targeting agents for semitelechelic
HPMA copolymers. (… -based drug delivery systems, with degradation of the disulfide bond on …
HPMA copolymers. (… -based drug delivery systems, with degradation of the disulfide bond on …
The Use of HPMA Copolymer Conjugates for the Intracellular Targeting of Anticancer Drugs
JD Callahan - 2017 - search.proquest.com
… to an HPMA-doxorubicin anticancer drug carrier. Monoclonal … Semitelechelic TPP-HPMA
copolymers were synthesized to … of TPP-functionalized semitelechelic HPMA copolymers ........…
copolymers were synthesized to … of TPP-functionalized semitelechelic HPMA copolymers ........…
Funtionalization of Pharmaceutical Nanocarriers for Mitochondria-Targeted Drug and DNA Delivery
V Weissig, S Boddapati, G D'Souza… - … Pharmaceutical …, 2008 - Springer
… nano drug carriers for mitochondrial-targeted drug and DNA … components of the mitochondrial
membrane and–depending on … triphenylphosphonium-bearing liposomes for mitochondria-…
membrane and–depending on … triphenylphosphonium-bearing liposomes for mitochondria-…
Design of smart HPMA copolymer-based nanomedicines
… in drug delivery, the design, synthesis and evaluation of drug-… possessing 4 mol% of
moderately hydrophobic functional … protection (usually a semitelechelic hydrophilic polymer) is …
moderately hydrophobic functional … protection (usually a semitelechelic hydrophilic polymer) is …
Multifunctional water-soluble polymers for drug delivery
H Pan, J Kopecek - Multifunctional pharmaceutical nanocarriers, 2008 - Springer
… Semitelechelic HPMA copolymers functionalized with triphenylphosphonium as drug carriers
for membrane transduction and mitochondrial localization. Biomacromolecules 7: 2347–…
for membrane transduction and mitochondrial localization. Biomacromolecules 7: 2347–…
Overcoming the barrier of CD8+ T cells: Two types of nano-sized carriers for siRNA transport
I Tabujew, M Willig, N Leber, C Freidel, I Negwer… - Acta Biomaterialia, 2019 - Elsevier
… functionality of the (HPMA-s-APMA)-b-GPMA block copolymer was cleaved to a free …
functionalization of cationic diblock copolymers with the uptake-promoting triphenylphosphonium …
functionalization of cationic diblock copolymers with the uptake-promoting triphenylphosphonium …
Molecular platforms for targeted drug delivery
… can also be achieved via the direct functionalization of the … -specific interactions with biological
membranes or other body … HPMA copolymers offer high drug loading capacity due to the …
membranes or other body … HPMA copolymers offer high drug loading capacity due to the …
Delivery of biologically active molecules to mitochondria
D Guzman-Villanueva, V Weissig - Mitochondrial Mechanisms of …, 2016 - Springer
… Due to these functional characteristics, mitochondria have … of triphenylphosphonium (TPP)
cations for selectively targeting … by the mitochondrial membrane potential, their delivery to the …
cations for selectively targeting … by the mitochondrial membrane potential, their delivery to the …
A pH-Activatable nanoparticle for dual-stage precisely mitochondria-targeted photodynamic anticancer therapy
… mitochondria-targeted drug delivery, a variety of nanoparticles decorated with targeting ligands
[22] including triphenylphosphonium (TPP) … The mitochondrial membrane potential was …
[22] including triphenylphosphonium (TPP) … The mitochondrial membrane potential was …