[PDF][PDF] Gene expression of serotonergic markers in peripheral blood mononuclear cells of patients with late-onset Alzheimer's disease

M Neshan, A Campbell, SK Malakouti, M Zareii… - Heliyon, 2020 - cell.com
… In support of this finding, Studies using various methods such as immunohistochemistry,
post-mortem, and imaging have all shown a reduction in brain 5-HTR2A density in patients with …

5-HT4 receptor agonists treatment reduces tau pathology and behavioral deficit in the PS19 mouse model of tauopathy

S Jiang, EJ Sydney, AM Runyan, R Serpe… - Frontiers in Cellular …, 2024 - frontiersin.org
… 633 individual dorsolateral prefrontal cortex samples. Mayo … in advanced Braak stages
in the AD post-mortem brains. … Immunohistochemical analyses of the hippocampus, shown …

Class A GPCR: serotonin receptors

E Grinde, K Herrick-Davis - G-Protein-Coupled Receptor Dimers, 2017 - Springer
… The 5-HT6 receptor is thought to play a role in learning and … expression levels and signaling
properties in post-mortem brainImmunohistochemical labeling studies have reported the co-…

The Neurophysiology and Behavioral Pharmacology of Memory Enhancement and Memory Deficits in the Dentate Gyrus

GJ Remigio - 2017 - search.proquest.com
… to other serotonin receptor subtypes, the 5-HT6 receptor has … of GABA in rat frontal
cortex, dorsal hippocampus, striatum, … and immunohistochemistry to dissect 5-HT6 receptor

TUNEL and growth factor expression in the prefrontal cortex of Alzheimer patients over 80 years old

DE Lorke, MSM Wai, Y Liang… - International Journal of …, 2010 - journals.sagepub.com
immunohistochemistry for … post-mortem neuropathological assessment of AD using established
criteria including Braak staging (29). Four brain regions were examined: prefrontal (area

Dopamine neurotransmission and atypical antipsychotics in prefrontal cortex: a critical review

M Masana Nadal, N Santana Ramos… - Current Topics In …, 2012 - diposit.ub.edu
… of multiple brain regions including the prefrontal cortex (PFC). … Histological studies using
immunohistochemistry and in situ … to decrease the level of 5-HT6 receptor expression in rats, the …

Cholinergic and Serotonergic Systems in Severe Dementia

SI Sharp, PT Francis, CG Ballard - Severe Dementia, 2006 - Wiley Online Library
… In comparison with AD, post-mortem studies have shown M1 receptorsreceptors in dementia
of Alzheimer type: a quantitative autoradiographic study of frontal cortex and hippocampus. …

[PDF][PDF] Neurodevelopmental mechanisms underlying brain disorders: from loss-of-gene function to behavioral endophenotypes

JS Witteveen - 2016 - repository.ubn.ru.nl
… Also, due to 5-HTT deficiency, increased activity at the 5-HT6 receptor affects proper cortical
… /or migration of prefrontal cortical neurons, we performed immunocytochemistry for both 5-…

Serotonergic imaging in Parkinson's disease

ER de Natale, H Wilson, M Politis - Progress in Brain Research, 2021 - Elsevier
Post-mortem studies have also demonstrated that PD patients show marked alterations of
the serotonergic terminals in the braincortex, posterior cingular cortex, and prefrontal cortex, …

Therapeutics of neurotransmitters in Alzheimer's disease

R Kandimalla, PH Reddy - Journal of Alzheimer's Disease, 2017 - content.iospress.com
… have been revealed with immunohistochemical observations in … also have a high density
of 5-HT6 receptors [145]. … levels in the frontal cortex, basal ganglia, and hippocampus. On the …