Observations with insulin on department of soldiers' civil Re-establishment diabetics

JA Gilchrist, CH Best, FG Banting - Canadian Medical Association …, 1923 - ncbi.nlm.nih.gov
… Therefore, the patient is desensitized by the subcutaneous … On injection there is local pain,
due to the cresol preservative… A comparison with the ferric chloride test, (which is sensitive to …

Additives: Preservatives, Antioxidants, Dyes, and Others

A Barbaud - Cutaneous Drug Hypersensitivity: Clinical Features …, 2022 - Springer
reactions occur due to the preservatives added to insulin, … in sulfite-sensitive asthmatics
with severe reactions. In vitro, it … In conclusion, intolerance to sulfites contained in drugs seems …

Role of Skin Mast Cells in the Usable Lifespan of Continuous Subcutaneous Insulin Infusion

S Kesserwan - 2022 - search.proquest.com
… in response to m-cresol and phenol excipients present in standard insulin formulations. The
… our initial hypothesis that IPP leads to MC activation which in turn leads to both acute and …

[HTML][HTML] Melatonin rescues mesenchymal stem cells from senescence induced by the uremic toxin p-cresol via inhibiting mTOR-dependent autophagy

SP Yun, YS Han, JH Lee, SM Kim… - Biomolecules & …, 2018 - ncbi.nlm.nih.gov
… senescence in patients with chronic kidney failure could be … , it has been shown that insulin
promoted the differentiation of … -induced MSC senescence is sensitive to the incubation with …

[PDF][PDF] Case Report Successful Management of Insulin Allergy and Autoimmune Polyendocrine Syndrome Type 4 with Desensitization Therapy and Glucocorticoid …

J Rojas, M Villalobos, MS Martínez, M Chávez-Castillo… - academia.edu
… added to insulin preparations such as cresol, protamine, and … -acting insulin (Crystalline)
due to type I hypersensitivity to … the need for skin prick testing and assessment of IgE-insulin-…

Targeting the gut‐skin axis—Probiotics as new tools for skin disorder management?

M Szántó, A Dózsa, D Antal, K Szabó… - Experimental …, 2019 - Wiley Online Library
… , free phenol and para-cresol, are considered as biomarkers of … sensitivity have been
associated with severe cutaneous … load drives the production of insulin and insulin-like growth …

Insulin analogs with improved pharmacokinetic profiles

J Brange, A Vølund - Advanced drug delivery reviews, 1999 - Elsevier
… in the presence of phenol or cresol molecules which make … the circulating insulin concentration
by sensitive and specific … This unexpected difference in a serious adverse effect led to …

Lipohypertrophy and Insulin. An Old Dog that Needs New Tricks

J Huang, AM Yeung, D Kerr, S Gentile, L Heinemann… - Endocrine Practice, 2023 - Elsevier
insulin therapy using impure insulin formulations, local skin … causing acute/chronic inflammation
and insulin degradation … of LH was not sufficiently sensitive or specific for widespread …

The skin reactions of infants and children to soaps

L Goldman - Journal of the American Medical Association, 1937 - jamanetwork.com
… solution of cresol as being responsible for skin reaction from soap… for testing the hyper¬
sensitive skin. Though there is some … per¬ sistent than with ordinary insulin, so that normal blood …

Bacterial metabolic 'toxins': a new mechanism for lactose and food intolerance, and irritable bowel syndrome

AK Campbell, SB Matthews, N Vassel, CD Cox… - Toxicology, 2010 - Elsevier
… or constipation, severe headaches, severe fatigue, loss of … toxins react with proteins and
other molecules, such as insulin… of putative bacterial toxins such as cresol on the health and …