Signal transduction of inflammatory cytokines and tumor development

A Yoshimura - Cancer science, 2006 - Wiley Online Library
… (NSAIDs) decreases cancer risk (a 40–50% reduction in the case of colon cancer) … signaling
network is the existence of extensive cross-talk between apoptosis, NF-κB and JNK signaling

The cross-talk between signaling pathways, noncoding RNAs and DNA damage response: emerging players in cancer progression

F Malakoti, F Alemi, S Younesi, M Majidinia, B Yousefi… - DNA repair, 2021 - Elsevier
… , have a significant function in the signal transduction step in the DDR pathway. A DNA …
cancer progression such as hepatocellular carcinoma, pancreatic and colorectal cancer through

Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling

X Yan, YG Chen - Biochemical Journal, 2011 - portlandpress.com
through activation of NF-κB or STAT1 (signal transducer and … pancreatic cancer, skin cancer,
scleroderma and lung cancer … of SMAD7 can influence the risk of colorectal cancer [135]. In …

TNF/VEGF cross-talk in chronic inflammation-related cancer initiation and progression: an early target in anticancer therapeutic strategy

F Guadagni, P Ferroni, R Palmirotta, I Portarena… - in vivo, 2007 - iv.iiarjournals.org
… , thus facilitating signal transduction through the rapid recruitment of … Serum IL-6 and TNF-alpha
levels in colorectal cancer … Kaplan-Meier survival analyses of colorectal cancer patients …

Cross-talk between miRNA and Notch signaling pathways in tumor development and progression

Z Wang, Y Li, D Kong, A Ahmad, S Banerjee, FH Sarkar - Cancer letters, 2010 - Elsevier
… , resulting in blocking the Notch signal transduction signaling [3]. … on Notch signaling in multiple
tissues, while others are tissue … found in malignant melanoma, colorectal cancer, and oral …

PanIN neuroendocrine cells promote tumorigenesis via neuronal cross-talk

S Sinha, YY Fu, A Grimont, M Ketcham, K Lafaro… - Cancer research, 2017 - AACR
… NK1-R + cells may serve as a source of Wnt ligands that are critical for PanIN tumorigenesis
(39) and that can depend on close cell contact for signal transduction (48). Interestingly, the …

[HTML][HTML] Cross-talk between Wnt signaling and Src tyrosine kinase

JK Min, HS Park, YB Lee, JG Kim, JI Kim, JB Park - Biomedicines, 2022 - mdpi.com
… Aberrant Wnt signaling as well as increased Src activity is closely related to many diseases.
… Wnt signaling in cancer progress has most prominently been described for colorectal cancer

Cancer-associated neurogenesis and nerve-cancer cross-talk

DA Silverman, VK Martinez, PM Dougherty, JN Myers… - Cancer research, 2021 - AACR
… found in glioma tissue and facilitate gap-junction signal transmission (88, 90). In addition, …
Cholinergic stimulation also prevents colorectal cancer progression by inducing trefoil factor …

[HTML][HTML] Role of tissue microenvironment resident adipocytes in colon cancer

M Tabuso, S Homer-Vanniasinkam… - World journal of …, 2017 - ncbi.nlm.nih.gov
cross-talk mechanisms between adipocytes and colonicsignalling pathways of both early
colonic carcinogenesis and … activator of Janus Kinase and signal transducers and activators of …

[HTML][HTML] CXCR4 and CXCR7 signaling pathways: a focus on the cross-talk between cancer cells and tumor microenvironment

S Santagata, C Ieranò, AM Trotta, A Capiluongo… - Frontiers in …, 2021 - frontiersin.org
… CXCL12 binding to CXCR4 triggers multiple signal transduction pathways that regulate …
EMT-signaling (36). CXCR7 mRNA and protein are overexpressed in colorectal cancer patients …