Sleep quality in efavirenz-treated Chinese HIV patients–comparing between GT and GG genotype of CYP2B6-516 G/T polymorphisms
… time and with adjustment of sleep time, longer term adverse … pattern of sleep problems in
EFV-treated Chinese HIV patients over … with plasma EFV levels and CYP2B6 516 G/T genotype. …
EFV-treated Chinese HIV patients over … with plasma EFV levels and CYP2B6 516 G/T genotype. …
Sleep quality in efavirenz-treated Chinese HIV patients-comparing between GT and GG genotype of CYP2B6-516 G/T polymorphisms.
LSS Lee ShuiShan, TKW To KinWang… - 2014 - cabidigitallibrary.org
… Seventy-two adult Chinese HIV-positive treatment-naïve patients were recruited in a study …
associations between CYP2B6 516 G/T polymorphisms and sleep quality following treatment …
associations between CYP2B6 516 G/T polymorphisms and sleep quality following treatment …
Meta-analysis of the associations of CYP2B6-516G> T polymorphisms with efavirenz-induced central nervous system side effects and virological outcome in HIV …
L Cheng, Y Wang, X Li, W Feng, B Weng… - The …, 2020 - nature.com
… association of CYP2B6-516 GT + TT and GG genotypes with … One study carried out among
a Chinese HIV-infected … , while sleep disturbance is recorded in nearly half of cases, and …
a Chinese HIV-infected … , while sleep disturbance is recorded in nearly half of cases, and …
Effects of rifampicin, CYP2B6 and ABCB1 polymorphisms on efavirenz plasma concentration in Chinese patients living with HIV and tuberculosis
L Zhang, X Meng, P Dong, T Qi… - … journal of STD & …, 2023 - journals.sagepub.com
… lower in patients with 516 GT and 785 GG genotypes in HIV/TB … significant in patients with
CYP2B6 785 GG genotype, while … obvious effects of the CYP2B6 516 G>T and 785 A>G gene …
CYP2B6 785 GG genotype, while … obvious effects of the CYP2B6 516 G>T and 785 A>G gene …
Polymorphisms at CYP enzymes, NR1I2 and NR1I3 in association with virologic response to antiretroviral therapy in Brazilian HIV-positive individuals
C de Almeida Velozo, TB de Almeida… - The …, 2022 - nature.com
… of ART ( adj HR = 0.32 for GG genotype and 0.62 for G carriers) (… All patients from our cohort
received ART regimens that … in Supplementary Table 5 for different biogeographical groups. …
received ART regimens that … in Supplementary Table 5 for different biogeographical groups. …
Case report: Severe central nervous system manifestations associated with aberrant efavirenz metabolism in children: the role of CYP2B6 genetic variation
E Abrams - 2015 - open.uct.ac.za
… Sleep quality in efavirenz-treated Chinese HIV patients - comparing between GT and GG
genotype of CYP2B6-516 G/T polymorphisms. Int J STD AIDS. 2014;25(3): 193–200. …
genotype of CYP2B6-516 G/T polymorphisms. Int J STD AIDS. 2014;25(3): 193–200. …
… of pharmacogenetics determinants of efavirenz response that includes 3′-UTR single nucleotide polymorphisms among Black South African HIV/AIDS patients
… (PXR) were selected for genotyping among 222 Bantu-speaking South African HIV-infected …
for each HIV/AIDS patient and median EFV plasma concentrations were compared between …
for each HIV/AIDS patient and median EFV plasma concentrations were compared between …
Case report: Severe central nervous system manifestations associated with aberrant efavirenz metabolism in children: the role of CYP2B6 genetic variation
F Pinillos, C Dandara, M Swart, R Strehlau… - BMC infectious …, 2015 - Springer
… carrying CYP2B6 single nucleotide polymorphisms, known to … < G/T < G/G and EFV levels
following the pattern T/T > G/T > … the CYP2B6 516 SNP alone would fail to predict the patients …
following the pattern T/T > G/T > … the CYP2B6 516 SNP alone would fail to predict the patients …
The impact of pharmacogenetics on HIV therapy
TW Mahungu, MA Johnson, A Owen… - … journal of STD & …, 2009 - journals.sagepub.com
… higher in patients with the 516TT genotype compared to those with the 516GG genotype. …
This coupled with a move away from polymorphisms analysed in isolation towards high …
This coupled with a move away from polymorphisms analysed in isolation towards high …
Effect of mid-dose efavirenz concentrations and CYP2B6 genotype on viral suppression in patients on first-line antiretroviral therapy
… HIV-RNA and efavirenz mid-dose interval concentrations … →T and 983T→C polymorphisms.
Cox proportional hazards … plate (Life Technologies, Beijing, China). DNA samples were left …
Cox proportional hazards … plate (Life Technologies, Beijing, China). DNA samples were left …