Recent advances in liposomal dry powder formulations: preparation and evaluation

A Misra, K Jinturkar, D Patel, J Lalani… - Expert opinion on drug …, 2009 - Taylor & Francis
… errors, slow inhalation at the start of the inhalation maneuver, … suitable analytical methods
such as HPLC or bioassays to … formeterol was developed to treat asthma using freeze-drying of …

Bioequivalence of inhaled corticosteroids—A pharmacokinetic approach

NS Goyal - 2009 - search.proquest.com
… in the above discussion that asthma is a disease of the … bioassay statistical procedures
were used to estimate the relative potency of the generic inhaler relative to the innovator inhaler […

Delivery of biotherapeutics by inhalation aerosol

RW Niven - Critical Reviews™ in Therapeutic Drug Carrier …, 1995 - dl.begellhouse.com
… in inhaler technology toward functional, reproducible devices … The initiation of new shelf
stability studies therefore will be … ,183 cystic fibrosis,184 and asthma,185 are all conditions that …

Development and approval of inhaled respiratory drugs: A US regulatory science perspective

GJP Singh, G Poochikian - Controlled Pulmonary Drug Delivery, 2011 - Springer
… powders in an inhaler [15]. Electrostatic forces also influence the … most asthma drugs is
bronchodilation and is primarily based … –response relationship which may vary with the bioassay, …

Evaluation and comparison of inhaled steroids

SJ SZEFLER, RJ MARTIN - Inhaled Steroids in Asthma …, 2001 - books.google.com
… -based propellant for a pressurized metered dose inhaler was … if the leukotriene antagonists
and other nonsteroid long-term … A bioassay for topical and systemic effect of three inhaled

[PDF][PDF] Development of a pulmonary technique to assess inhaled bronchoactive agents in the conscious rhesus monkey.

RM Weissberg, JB Bradshaw, GL Garay - Journal of Pharmacology and …, 1978 - Citeseer
… Aerosolized antagonists, given in increasing doses, were … 5 times more effective than
salbutamol in blocking histamine-… to evaluate both bronchodilator and irritational properties of …

β2-Adrenergic receptor agonists activate CFTR in intestinal organoids and subjects with cystic fibrosis

LAW Vijftigschild, G Berkers, JF Dekkers… - European …, 2016 - Eur Respiratory Soc
inhaled salbutamol. One patient was only treated with oral salbutamol due to increased
asthma … of plasma levels of salbutamol in our organoid-based bioassay. The study supports the …

Urinary Pharmacokinetic Methodology to Determine the Relative Lung Bioavailability of Inhaled Beclometasone

A Said - 2011 - eprints.hud.ac.uk
Urinary pharmacokinetic methods have been introduced to identify the relative lung and
systemic availability of inhaled drugs but have not been extended to corticosteroids. The main …

Efficacy and mechanisms of action of traditional Chinese medicines for treating asthma and allergy

XM Li, LV Brown - Journal of Allergy and Clinical Immunology, 2009 - Elsevier
… -4 antagonist, has showed some benefits on asthma in initial … 6 to 12 hours after allergen
inhalation and is associated with … Our group has conducted a systematic bioassay-guided …

An evaluation of the Bronchodilator properties of Mentha longifolia and Artemisia afra, traditional medicinal plants used in the Western Cape.

L Harris - 2002 - etd.uwc.ac.za
… Evaluation of asthma medication using animals Techniques to … strip preparations Experimental
protocol of tracheal strip bioassay … When administered by inhalation these agents start