… and during experimental infection (4). … polymerization of phenolic and/or indolic compounds
(15), and the pigments are found in all biological kingdoms (2). Melanin synthesis occurs in C…

… for the biosynthesis of melanin. Disruption of LAC1 was observed to significantly prolong the
survival of infected mice … by oxidative polymerization of phenolic and/or indolic compounds. …

… that can serve as a precursor for cryptococcal melanin biosynthesis [58]. Another study …
was established by the finding that mice pre-treated with antibiotics prior to infection with C. …

… Toxoplasma gondii-infected mice is resistant to subsequent infection with C. … In general,
the last step in melanin synthesis is not enzymatic but a spontaneous polymerization (Bell and …

… melanin synthesis have been implicated as contributors to virulence in Cryptococcus
neoformans… or aminophenols are oxidatively polymerized by the laccase enzyme and deposited …

… intermediates produced during melanin biosynthesis [13], and … , the protein that catalyses
melanin polymerization. There was … of Cryptococcus neoformans and prolongs survival of mice …

… formed by oxidative polymerization of phenolic or indolic … Cryptococcus neoformans is
probably the most prominent of … neoformans is in fact incapable of de novo melanin synthesis…

… in vitro-melanized Cryptococcus neoformans cells and Aspergillus niger … These pigments
are synthesized by organisms … to increase the rate of polymerization into melanin. However, …

… These black pigments are produced by uninhibited polymerization of … neoformans that
caused a chronic 3-month infection in mice (… Melanin biosynthesis in Cryptococcus neoformans …

… Although melanin biosynthesis has been portrayed as proceeding via oxidative
polymerization of l-dopa, our spectroscopic analyses underscore the incomplete nature of this …