NKT agonist-antigen conjugates as cancer vaccines

BJ Compton, GF Painter - Critical Reviews™ in Oncogenesis, 2024 - dl.begellhouse.com
… of CD40L that activate antigen-presenting cells (APCs) … cell targeted agonist-antigen
conjugate vaccines can elicit … IgG antibody response elicited by a fully synthetic two-component …

Antibody-targeted vaccines

T Keler, L He, V Ramakrishna, B Champion - Oncogene, 2007 - nature.com
… of antigens to professional antigen-presenting cells (APCs) with … responses and antitumor
activity in the MR-tg mice. Strong … Recently, the use of ATVs to elicit protective and therapeutic …

RNA based vaccines

G Cannon, D Weissman - DNA and cell biology, 2002 - liebertpub.com
Antigen presenting cells (APC) encounter most protein and vaccine … For the first strand
synthesis, it was primed by an … of CD4+ T-cell help necessary for eliciting long term CD8+ cytolytic …

… novel dendritic cell-targeted lentiviral vector, encoding Ag85A-ESAT6 fusion gene of Mycobacterium tuberculosis, could elicit potent cell-mediated immune responses …

M Shakouri, SM Moazzeni, M Ghanei, A Arashkia… - Molecular …, 2016 - Elsevier
… Dendritic Cells (DCs) are potent antigen presenting cells, … to boost the disappearing protective
response in individual who … removed and replaced with a synthetic fragment (BAP), as it …

Dendritic Cell Targeting Using a DNA Vaccine Induces Specific Antibodies and CD4+ T Cells to the Dengue Virus Envelope Protein Domain III

AB Zaneti, MM Yamamoto, FB Sulczewski… - Frontiers in …, 2019 - frontiersin.org
… to dendritic cells (DCs), the main antigen presenting cells and … was able to elicit a polyfunctional
CD4 + T cell response. … NS1 protein induced protection via CD4 + T cells and antibodies …

[HTML][HTML] Targeting CLEC9A delivers antigen to human CD141+ DC for CD4+ and CD8+ T cell recognition

KM Tullett, IML Rojas, Y Minoda, PS Tan, JG Zhang… - JCI insight, 2016 - ncbi.nlm.nih.gov
… Given the importance of these cellular responses for antitumor … professional antigen-presenting
(Ag-presenting) cells that … .1 + were generated by gene synthesis of codon-optimized …

Enhancing antitumor immune responses by optimized combinations of cell-penetrating peptide-based vaccines and adjuvants

E Belnoue, W Di Berardino-Besson, H Gaertner… - Molecular Therapy, 2016 - cell.com
… antigens to antigen-presenting cells such as dendritic cells (DCs… and Pam3CSK4 elicited
CD4 T cell immune responses at a … cell immunity together with a dendritic cell targeted vaccine. …

In vivo manipulation of dendritic cells to induce therapeutic immunity

M Merad, T Sugie, EG Engleman… - Blood, The Journal of …, 2002 - ashpublications.org
… provide the basis for dendritic cell- targeted clinical strategies. … cells (DCs) represent the
most potent antigen-presenting … of OVA induced a protective antitumor response and also led to …

[HTML][HTML] Nanodrugs targeting T cells in tumor therapy

M Haist, V Mailänder, M Bros - Frontiers in Immunology, 2022 - frontiersin.org
cells directly or to address antigen presenting cells (APC) like dendritic cells (DC) in order to
elicit tumor antigen-specific T … are attached to nano-sized beads, termed artificial (a)APC (9). …

Bioconjugation approaches to producing subunit vaccines composed of protein or peptide antigens and covalently attached toll-like receptor ligands

Z Xu, PM Moyle - Bioconjugate chemistry, 2017 - ACS Publications
elicit poor immunological responses, necessitating the use of adjuvants. Immunostimulatory
adjuvants have the capacity to activate antigen presenting cells … of synthetic approaches is …