Engineered nanoparticles for cancer vaccination and immunotherapy
… of tumor antigens as immune targets while exploiting … to lymph nodes, generating strong
antitumor T cell immunity. … able to elicit antitumor immunity against disseminated tumors…
antitumor T cell immunity. … able to elicit antitumor immunity against disseminated tumors…
[HTML][HTML] Nanoparticle drug delivery systems designed to improve cancer vaccines and immunotherapy
… by targeting nanovaccines to tumor-draining lymph nodes … microbubbles to allow
ultrasound-triggered transfection of DCs. … designed to elicit anti-tumoral immune responses. In …
ultrasound-triggered transfection of DCs. … designed to elicit anti-tumoral immune responses. In …
[HTML][HTML] Nanoparticle delivery of immunostimulatory agents for cancer immunotherapy
… promising means of elevating antitumor immunity. Here, we … of nanoparticles, thus enhancing
uptake efficiency by target … help to enhance nanoparticle localization in the lymph nodes, …
uptake efficiency by target … help to enhance nanoparticle localization in the lymph nodes, …
Nanoparticle‐based nanomedicines to promote cancer immunotherapy: recent advances and future directions
… but significantly enhance the antitumor immunity. … in PLGA nanoparticles migrated to draining
lymph nodes and … The TDLNs-targeted nanoparticles increased the amount of cytokines IL-…
lymph nodes and … The TDLNs-targeted nanoparticles increased the amount of cytokines IL-…
Nanotechnology-based approaches to promote lymph node targeted delivery of cancer vaccines
R He, J Zang, Y Zhao, H Dong, Y Li - ACS Biomaterials Science & …, 2022 - ACS Publications
… inhibits and eliminates cancer by activating the immune system. … vaccines to reactivate
antitumor immune response and … or chemical synthesis, achieve the specific targeting with locally …
antitumor immune response and … or chemical synthesis, achieve the specific targeting with locally …
[HTML][HTML] Biodegradable polymeric nanoparticles-based vaccine adjuvants for lymph nodes targeting
A Gutjahr, C Phelip, AL Coolen, C Monge, AS Boisgard… - Vaccines, 2016 - mdpi.com
… We point out how these nanoparticles enhance the delivery of … However, nanoparticles
seem to be able to trigger either … Synthetic vaccine particles co-encapsulating a model antigen …
seem to be able to trigger either … Synthetic vaccine particles co-encapsulating a model antigen …
Efficient nanovaccine delivery in cancer immunotherapy
… secondary lymphoid organs such as lymph nodes (LNs) and … induce optimal antitumor
immunity. Adjuvants induce robust … Nanovaccines have been developed for LN-targeted delivery …
immunity. Adjuvants induce robust … Nanovaccines have been developed for LN-targeted delivery …
Emerging advances in synthetic cancer nano-vaccines: opportunities and challenges
… Nanoparticles (NPs) vaccine delivery … a better target to an effective immune response.
They can be quickly drained via lymphatic systems to lymph nodes, which is full of immune cells. …
They can be quickly drained via lymphatic systems to lymph nodes, which is full of immune cells. …
Mannan-decorated pathogen-like polymeric nanoparticles as nanovaccine carriers for eliciting superior anticancer immunity
Y Xu, S Ma, J Zhao, H Chen, X Si, Z Huang, Z Yu… - Biomaterials, 2022 - Elsevier
… synergize with CpG for maximally activating the DCs. Excitingly… role in the lymph node drainage
of nanoparticles, with sizes … Besides, decorating particles with actively targeting moieties, …
of nanoparticles, with sizes … Besides, decorating particles with actively targeting moieties, …
Nanoparticles for tumor immunotherapy
X Zang, X Zhao, H Hu, M Qiao, Y Deng… - European Journal of …, 2017 - Elsevier
… However, antitumor immunity driven by self-immune system … to target DCs in lymphatic
nodes. They found that 20 nm … Likewise, nanoparticulate aAPCs aimed at directly activating T …
nodes. They found that 20 nm … Likewise, nanoparticulate aAPCs aimed at directly activating T …