Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and …

LH Ping, SB Joseph, JA Anderson… - Journal of …, 2013 - Am Soc Microbiol
… evidence indicates that macrophage tropism is not required … criterion of a CD4 + T cell count
between 200 and 500 cells/μl… Env conformation associated with culture-adapted viruses (72)…

Identification of human immunodeficiency virus envelope gene sequences influencing viral entry into CD4-positive HeLa cells, T-leukemia cells, and macrophages

B Chesebro, J Nishio, S Perryman, A Cann… - Journal of …, 1991 - Am Soc Microbiol
… Conversely, many HIV strains have been adapted to … Macrophage tropism appeared to be
more complex than tropism for … Human immunodeficiency virus type 1 T-cell tropism is deter…

Coreceptor switch in R5-tropic simian/human immunodeficiency virus-infected macaques

S Ho, S Tasca, L Shek, A Li, A Gettie… - Journal of …, 2007 - Am Soc Microbiol
… with gradual peripheral CD4 + T cell effects, while X4 SHIV … We suggest that adaptation to
efficient usage of CXCR4 … molecular clone expressing the SF162 envelope in RM requires …

Mucosal Transmission and Induction of Simian AIDS by CCR5-Specific Simian/Human Immunodeficiency Virus SHIVSF162P3

JM Harouse, A Gettie, T Eshetu, RCH Tan… - Journal of …, 2001 - Am Soc Microbiol
… This dramatic loss in the CD4 + T-cell population is likely to be related to the coreceptor …
serial passage adaptation experiment of SHIV SF162 , a virus that contains thetat, rev, vpu, and …

Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: evidence for limited defectiveness …

Y Li, H Hui, CJ Burgess, RW Price, PM Sharp… - Journal of …, 1992 - Am Soc Microbiol
… nine T-cell line-adapted North American/European viruses in … the vpu ATG start codon in
HIV-1YU-2 In the case of vpu, we … zinc in human immunodeficiency virus type 1, human T-cell

Emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants in a minority of HIV-1-infected patients following treatment with the CCR5 …

M Westby, M Lewis, J Whitcomb, M Youle… - Journal of …, 2006 - Am Soc Microbiol
… the effect of short-term monotherapy with maraviroc on viral load … the purified envelope
expression vector library and an HIV-1 … of CCR5-tropic HIV-1 strains suggest that the molecular …

Role of low CD4 levels in the influence of human immunodeficiency virus type 1 envelope V1 and V2 regions on entry and spread in macrophages

BL Walter, K Wehrly, R Swanstrom, E Platt… - Journal of …, 2005 - Am Soc Microbiol
… In HIV-1 isolates adapted to growth in microglia, V1 and V2 … macrophage tropism from an
exclusively T-cell-tropic simian … /V2 region influences macrophage tropism, microglial tropism…

Intrinsic obstacles to human immunodeficiency virus type 1 coreceptor switching

C Pastore, A Ramos, DE Mosier - Journal of virology, 2004 - Am Soc Microbiol
human immunodeficiency virus type 1 (HIV-1) into target cells requires binding of the viral
envelope glycoprotein gp120 to CD4 and one … NSI) viruses, and R5X4 or X4 isolates are T-cell-…

Virological control by the CD4-binding site antibody N6 in simian-human immunodeficiency virus-infected rhesus monkeys

B Julg, A Pegu, P Abbink, J Liu, A Brinkman… - Journal of …, 2017 - Am Soc Microbiol
… of the human immunodeficiency virus type 1 (HIV-1) envelope … -specific CD8 + T-cell responses
following bnAb treatment. … as being characteristic of SF162 viruses that had undergone a …

Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor …

M Westby, C Smith-Burchnell, J Mori, M Lewis… - Journal of …, 2007 - Am Soc Microbiol
… The SF162 strain acquired resistance to maraviroc in both treated … The CD4 + T-cell clone
PM1 was obtained from the … maraviroc-resistant virus with laboratory-adapted HIV-1 strain Ba-…