… a retrovirus [human immunodeficiency virus type 1 (HIV-1)] … In vivo, the loss of macrophage
tropism by one viral variant was … To mimic the T cell-insufficient paradigm of AIDS, we infected …

… ) against viral envelope proteins (Env) provide the first line of … clade B primary viruses and
T-cell line-adapted virus strains (… : excluding the sensitive viruses HXB2r, MN, SF162, and NL4…

… Human immunodeficiency virus envelope glycoprotein/CD4-mediated fusion of nonprimate
… involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains …

… line resulted in an in vitro adapted HIV-1 derivative (NL-DT5R), which replicated well in the
CM T-cell line (… region of simian immunodeficiency virus SIVgsn166 vpu. The resultant clone, …

… , HIV-2 does not express Vpu but has adapted its envelope (Env) … 2693BA and the HIV-2
strain 7312 showed smaller effects (… Human immunodeficiency virus type 1 (HIV-1) AD8-infected …

… Human Immunodeficiency Virus type 1 (HIV-1) isolates can be … Macrophage-T cell(MT)-tropic
isolates (eg HIV-1 strain BaL) … neutralization is correlated with their macrophage tropism. …

… Binding of the envelope glycoprotein (Env) of HIV-1 to these … One of the consequences of
this genetic diversity is that HIV-l … Strains that infect T cell lines (T cell line adapted) but are …

… Human immunodeficiency virus type 1(HTV-1) belongs to the … for X4-tropic, T-cell line adapted
HTV-1. However, these … gpl20 can affect the T-cell-line and macrophage tropism of human …

… neutralized T-cell line adapted strain of HIV-1. This data indicates that macrophage-tropism
in … The Human Immunodeficiency Virus (HIV) is an enveloped virus with glycoprotein spikes …

… Laboratory-adapted HIV-1 strains were initially tested in … on elucidating viral determinants
of macrophage tropism, since the … has a major impact on the kinetics of CD4+ T-cell depletion, …