… We aim to clarify the concept of biosimilar, from … a literature search on the sites of the
medicines regulatory agencies and PubMed from 1990 to 2014 with the keywords “biosimilars,” “…

… To conduct and explore this review, we mainly followed the PRISMA guidelines for systematic
reviews [18], although “state of the art” methodology was also used. To identify relevant …

… efficacy and safety data on biosimilars. This review summarizes the recent updates on
biosimilars, synthesis, characterization, and current market status. Brief information on the role of …

… The designation of biosimilars is defined in relation to a reference product in an FDA
licensure … The concept of biosimilars: from characterization to evolution— a narrative review. …

… explore this review, we mainly followed the PRISMA guidelines for systematic reviews [18], …
Preferred reporting items for systematic review and meta-analysis protocols (prisma-p) 2015…

… investigates the transformative computer-aided discovery techniques for biosimilar agents
… rise of cost-effective biosimilars as alternatives to biologics. Through this analysis, this study …

… The key characteristics of these molecules, known as critical quality … be characterized for
the originator molecule and systematically matched as closely as possible by the biosimilar …

… efficacy and safety can clearly be deduced from the similarity of physicochemical
characteristics, biological activity/potency, and PK and/or PD profiles of the biosimilar and the RP. …

… Even though generic drugs and biosimilars are both copies of a reference drug, they differ
… , this short review aims to compare generic drugs and biosimilars in terms of characteristics, …

… biologics and their respective biosimilars, compatibility and characterization studies must be
… SK conceived and designed the review. SK, AP and EK performed the literature review. All …