[HTML][HTML] Identification of potential repurposable drugs in alzheimer's disease exploiting a bioinformatics analysis
… to prevent or restore memory deficit, as observed in a mouse model of AD [… reduce Amyloid
β and tau pathologies in mice [48]. … -sensitive potassium channel opener, diazoxide has been …
β and tau pathologies in mice [48]. … -sensitive potassium channel opener, diazoxide has been …
Levosimendan ameliorates the scopolamine induced cognitive impairment via modulating pCREB/BDNF expression, cholinergic neurotransmission and …
AS Kolusu, GS Ganesh, M Nagabhairava… - 2023 - researchsquare.com
… via activation of BACE-1 enzyme, Amyloid-β accumulation, … Alzheimer’s-like
scopolamine-induced amnesic mice model. … Pathologies and Improves Memory in the 3xTgAD …
scopolamine-induced amnesic mice model. … Pathologies and Improves Memory in the 3xTgAD …
Antimicrobial properties of amyloid peptides
… A number of different factors can contribute to the formation of amyloid β-sheet structures …
and tau pathology in a transgenic AD mouse model. Diazoxide, a potassium channel opener…
and tau pathology in a transgenic AD mouse model. Diazoxide, a potassium channel opener…
Prospective of managing impaired brain insulin signalling in late onset Alzheimers disease with excisting diabetic drugs
GM Jojo, G Kuppusamy, K Selvaraj… - … & Metabolic Disorders, 2019 - Springer
… murine model of leptin-resistant obese mice ameliorated … amelioration of Aβ and tau pathology
along with memory enhancement upon treatment with KATP channel activator-diazoxide […
along with memory enhancement upon treatment with KATP channel activator-diazoxide […
Inhibition of β-amyloid channels with a drug candidate wgx-50 revealed by molecular dynamics simulations
… (37) Additionally, diazoxide, a potassium ATP channel activator, was reported to improve
memory … in the cortex and hippocampus in a mouse model with AD in in vivo experiments by …
memory … in the cortex and hippocampus in a mouse model with AD in in vivo experiments by …
Repeated electromagnetic field stimulation lowers amyloid-β peptide levels in primary human mixed brain tissue cultures
… The KATP channel activator diazoxide ameliorates amyloid-β and Tau pathologies and
improves memory in the 3xTgAD mouse model of Alzheimer’s disease. J. …
improves memory in the 3xTgAD mouse model of Alzheimer’s disease. J. …
[HTML][HTML] Mitochondrial small conductance SK2 channels prevent glutamate-induced oxytosis and mitochondrial dysfunction
… The K ATP channel activator diazoxide ameliorates amyloid-β and tau pathologies and
improves memory in the 3xTgAD mouse model of Alzheimer's disease. …
improves memory in the 3xTgAD mouse model of Alzheimer's disease. …
… , safety and efficacy of the use of intravenous infusions of adenosine triphosphate (atp) in people affected by moderate to severe alzheimer's disease: A double-blind …
A Ruiz, D Sánchez, A Lafuente, G Ortega… - … of Alzheimer's Disease, 2022 - Springer
… protein precursor, being the characteristic amyloid-β plaques … in AD mice models with the
KATP agonist diazoxide suggest that … of KATP channels also decreased the memory disorders, …
KATP agonist diazoxide suggest that … of KATP channels also decreased the memory disorders, …
Potential therapeutic strategies to prevent the progression of alzheimer to disease states
E Aso, I Ferrer - Understanding Alzheimer's Disease, 2013 - books.google.com
… in the treatment of AD, as KATP channels are activated when cellular ATP … diazoxide
improves neuronal bioen‐ergetics, suppresses Aβ and tau pathologies, and ameliorates memory …
improves neuronal bioen‐ergetics, suppresses Aβ and tau pathologies, and ameliorates memory …
Membrane pores in the pathogenesis of neurodegenerative disease
BL Kagan - Progress in molecular biology and translational …, 2012 - Elsevier
… ameliorate Aβ-induced toxicity. Liu et al. reported … diazoxide, a K-ATP channel opener,
improved memory and decreased Aβ and tau levels in a transgenic mouse model of Alzheimer's …
improved memory and decreased Aβ and tau levels in a transgenic mouse model of Alzheimer's …