… in children with underlying predisposing conditions, such as … of disease causing serotypes
in the North America, Europe, … in the Southern Cone of South America) prior to PCV7 …

… serotype and more dependent on host-related factors. A major risk factor for death in
children with IPD is the presence of underlying comorbidities. We have previously reported that, …

… Invasive meningococcal disease (IMD) is one of the most feared infectious diseases in
children … We have described the current burden of IMD in a high-income European country with …

… underlying condition), because of few studies on this subject. We only analyzed the pooled
… an analysis of the case-fatality rate and risk factors for IPD. The findings of this study show …

… any underlying source of heterogeneity on the effect of childhood PCVs … North American
and European countries experienced similar changes for both invasive pneumococcal disease …

… and most European countries follow a 2 + 1 schedule. The reasons behind the differences
… distribution of risk factors, local transmission dynamics of pneumococcal serotypes, vaccine …

… First, heterogeneity in the underlying neighbourhood … is a risk factor for the development
of invasive disease [33, 34… pneumoniae isolates in young children in Europe: impact of …

… of underlying diseases with age may not be a specific risk … from 80% in the US to 30–40%
in Europe in children under 5 year-… characteristics, mortality rates, and risk factors are not the …

… nonsusceptibility were risk factors for mortality in Europe. A … of children with invasive
pneumococcal disease in different age … Though the underlying disease was no risk factor in the …

… million children die annually from pneumococcal disease, … including HIV-1 infection are
well-known risk factors associated with an … pathogens in patients with underlying comorbidity. We …