… higher risk of IPD in individuals with underlying disease can … also evidenced among adults
in Europe [30] and the USA [17]. … Not similarly, in North America, the most common serotypes …

… the risk of invasive pneumococcal disease in children … more quickly in persons with certain
underlying illnesses. In … in the United States and Europe, immunocompetent adults age 50 …

… of invasive pneumococcal disease among persons aged ≥65 years in North America and
Europe … Differences in the prevalence of these risk factors within a given population doubtless …

… and underlying illnesses. … risk factor for invasive pneumococcal disease in children,17 and
the large number of cases in this study with potential medical risk factors for invasive disease …

… A 10-year invasive pneumococcal disease (IPD) enhanced … total of 2691 Streptococcus
pneumoniae isolates from all ages … in the Oxfordshire region has identified this European clone (…

… other predisposing risk factors for pneumococcal disease. The … report risk-based guidelines
(depending on the underlying … implementation of childhood pneumococcal immunization in …

… Vaccinated children under 5 years of age had a higher risk of disease due … 8 was associated
with the presence of underlying risk factors. … Pneumococcal disease surveillance in Europe …

… of all children <2 years of age with 7-valent pneumococcal … to children with risk factors in most
European countries. … was the relatively low rate of underlying comorbidities we found in the …

… to be a risk factor for IPD in children 0–23 months of age, both before and after introduction
of PCV7. In children 6–23 months of age, the risk for IPD in preterm and full-term children was …

… Therefore, children with risk factors, aged 2–14 years, could … to establish the local burden of
pneumococcal disease and to assess … Meningitis and other invasive pneumococcal diseases …