Peroxisome proliferatoractivated receptor activators target human endothelial cells to inhibit leukocyte–endothelial cell interaction

SM Jackson, F Parhami, XP Xi, JA Berliner… - … , and vascular biology, 1999 - Am Heart Assoc
… Nonsteroidal anti-inflammatory agents and glucocorticoids … The prostaglandin-like PPAR
ligand 15d-PGJ 2 , a … that endows it with some antioxidant properties, 37 perhaps partially …

[HTML][HTML] PPARs in the renal regulation of systemic blood pressure

T Rőszer, M Ricote - Ppar Research, 2010 - ncbi.nlm.nih.gov
… roles for the peroxisome proliferator activated receptor (PPAR) … use of PPAR ligands.
PPARα and PPARγ modulate the renin-… In streptozotocin-induced diabetes in rats, the PPARα …

Diabetes, oxidative stress and therapeutic strategies

L Rochette, M Zeller, Y Cottin, C Vergely - Biochimica et Biophysica Acta …, 2014 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are … 1 diabetes (streptozotocin-induced
diabetic rats and Ins2 Akita … pro- and/or anti-inflammatory mediators to modulate metabolite …

[PDF][PDF] The role of PPARgamma in cardiovascular diseases

M Kvandová, M Majzúnová, I Dovinová - Physiol Res, 2016 - academia.edu
Peroxisome proliferator-activated receptors (PPAR) belong … In streptozotocininduced
diabetes in rats, bezafibrate and PIO … type 2 diabetic patients by the anti-inflammatory and …

The inhibitory effects of rosiglitazone on cardiac hypertrophy through modulating the renin‐angiotensin system in diet‐induced hypercholesterolemic rats

L Ren, Y Li, Y Li, R Tang, D Hu… - Cell Biochemistry and …, 2010 - Wiley Online Library
peroxisome proliferator-activated receptor-g (PPARg) ligand agonists attenuate cardiac
hypertrophy through antiinflammatory effects… are used as an anti-diabetic drug. This category of …

Spironolactone exhibits direct renoprotective effects and inhibits renal renin–angiotensin–aldosterone system in diabetic rats

M Taira, H Toba, M Murakami, I Iga, R Serizawa… - European journal of …, 2008 - Elsevier
… blood pressure in uninephrectomized streptozotocin-induced diabetic rats. These … direct
antioxidative and anti-inflammatory effects of peroxisome proliferator-activated receptors ligands

PPAR-δ: A key nuclear receptor in vascular function and remodeling

L Xiao, N Wang - Journal of Molecular and Cellular Cardiology, 2022 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are … diabetic db/db mice [38],
streptozotocin-induced diabetic rats [39]… while enhanced the expression of anti-inflammatory

Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Agonist Improves Coronary Artery Endothelial Function in Diabetic Patients with Coronary Artery Disease

J Yu, Z Zhang, Z Li, X Feng, L He… - Journal of …, 2010 - journals.sagepub.com
… metabolic effects, rosiglitazone, via its anti-inflammatory effects, may … function in the
aorta of streptozotocin-induced diabetic rats.… arteriolar endothelial function through an anti-oxidative

[HTML][HTML] Peroxisome proliferator-activated receptors and the heart: lessons from the past and future directions

WS Lee, J Kim - PPAR research, 2015 - hindawi.com
… (PPARs) belong to the nuclear family of ligand activated … -𝛼expression has anti-inflammatory
and antioxidative effects, and … in the heart of streptozotocin-induced diabetic rats,” Journal …

Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferatoractivated receptor-γ activators

V Pasceri, HD Wu, JT Willerson, ETH Yeh - Circulation, 2000 - Am Heart Assoc
… We found that several PPARγ activators inhibit expression of … ICAM-1 and α4 integrin (the
natural ligand for VCAM-1). We … has antioxidant effects, and the beneficial effects observed in …