Colchicine, biologic agents and more for the treatment of familial mediterranean fever. The old, the new, and the rare

P Portincasa - Current medicinal chemistry, 2016 - ingentaconnect.com
effectiveness of biologic agents working as TNF-α inhibitors (… colchicine in children and
adolescents with symptomatic FMF … colchicine-resistant pediatric patients initiated the etanercept

Conventional and novel therapeutic options in children with familial Mediterranean fever: A rare autoinflammatory disease

D Poddighe, M Romano… - British journal of …, 2022 - Wiley Online Library
… more frequent in the colchicine-resistant group (97% vs 68% in … of CNK for FMF adults,
adolescents and children aged 2 years and … started etanercept (0.8 mg/kg/week). The therapy with …

IL-1β biological treatment of familial Mediterranean fever

A Soriano, E Verecchia, A Afeltra, R Landolfi… - Clinical Reviews in …, 2013 - Springer
Familial Mediterranean fever (FMF) is a recessive, autosomal, auto-inflammatory disorder
characterised by brief, recurring, self-limited episodes of fever and serositis resulting in …

Anti-IL1 treatment in colchicine-resistant paediatric FMF patients: real life data from the HELIOS registry

E Sag, F Akal, E Atalay, UK Akca, S Demir… - …, 2020 - academic.oup.com
Anakinra and canakinumab are efficient and safe … In this study we aimed to investigate
the efficacy and safety of anti-… Four adolescent female who had FMF attacks only during the …

The efficacy, safety and tolerability of canakinumab in the treatment of familial Mediterranean fever: a systematic review of the literature

M Kacar, S Savic, JCH van der Hilst - Journal of inflammation …, 2020 - Taylor & Francis
… in colchicine-resistant FMF (crFMF) patients since the beginning of this century. Citation8
Anakinra, a … effective and safe in patients with colchicine-resistant or colchicine-intolerant FMF. …

Treat-to-target strategies for the management of familial Mediterranean Fever in children

L Ehlers, E Rolfes, M Lieber, D Müller, E Lainka… - Pediatric …, 2023 - Springer
… for autoinflammatory syndromes in children and adolescents (AID-NET) … The efficacy of
IL-1-blocking drugs in colchicine-resistant FMF (… While comparative trials between anakinra and …

An “On Demand” canakinumab regimen for treating children with Colchicine-Resistant familial Mediterranean fever–A multicentre study

K Shehadeh, Y Levinsky, S Kagan, T Zuabi… - International …, 2024 - Elsevier
… and efficacy in preventing familial Mediterranean fever (FMF) attacks among individuals with
colchicine-resistant (… In that study, anakinra was administered during prominent prodrome or …

Rilonacept for colchicine-resistant or-intolerant familial Mediterranean fever: a randomized trial

PJ Hashkes, SJ Spalding, EH Giannini… - Annals of internal …, 2012 - acpjournals.org
… study were to assess the efficacy of rilonacept in decreasing … have been used for
colchicine-resistant FMF, including tumor … anakinra, 4 weeks for etanercept, and 8 weeks for …

Anti-IL-1 treatment in familial Mediterranean fever and related amyloidosis

ZB Özçakar, S Özdel, S Yılmaz, ED Kurt-Şükür… - Clinical …, 2016 - Springer
colchicine-resistant FMF patients and patients with amyloidosis during childhood and adolescent
… After anakinra or canakinumab therapy, their lives completely changed without any or …

Interleukin-1 targeting drugs in familial Mediterranean fever: a case series and a review of the literature

U Meinzer, P Quartier, JF Alexandra, V Hentgen… - Seminars in arthritis and …, 2011 - Elsevier
Anakinra for the treatment of colchicine-resistant FMF has also been reported to be efficacious
… Colchicine use in children and adolescents with familial mediterranean fever: literature …