The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes
K Sahlholm, J Nilsson, D Marcellino, K Fuxe… - European journal of …, 2007 - Elsevier
… The histamine H 3 receptor mediates inhibitory responses in the … the human histamine H 3
receptor to G protein-coupled inward rectifier potassium (GIRK) channels in Xenopus oocytes, …
receptor to G protein-coupled inward rectifier potassium (GIRK) channels in Xenopus oocytes, …
Electrophysiology-based analysis of human histamine H4 receptor pharmacology using GIRK channel coupling in Xenopus oocytes
K Sahlholm, J Nilsson, D Marcellino, K Fuxe… - European journal of …, 2008 - Elsevier
… The histamine H 4 receptor couples via pertussis toxin-sensitive G i/o proteins and has
been shown to induce calcium mobilization, mitogen-activated protein kinase stimulation and …
been shown to induce calcium mobilization, mitogen-activated protein kinase stimulation and …
Histamine Receptors: Ex Vivo Functional Studies Enabling the Discovery of Hits and Pathways
A Seldeslachts, S Peigneur, J Tytgat - Membranes, 2023 - mdpi.com
… GIRK channels are members of a family of inwardly rectifying … of histamine receptors in
Xenopus Laevis oocytes, human H1… to couple with the inward rectifier potassium channels GIRK1/…
Xenopus Laevis oocytes, human H1… to couple with the inward rectifier potassium channels GIRK1/…
[HTML][HTML] Voltage sensitivities and deactivation kinetics of histamine H3 and H4 receptors
K Sahlholm, J Nilsson, D Marcellino, K Fuxe… - Biochimica et Biophysica …, 2012 - Elsevier
… We previously demonstrated both hH 3 445 and hH 4 receptors to activate GIRK
channels when coexpressed in Xenopus oocytes [28], [29]. In the present study, we used the …
channels when coexpressed in Xenopus oocytes [28], [29]. In the present study, we used the …
Histamine H3 Receptor Activation Modulates Glutamate Release in the Corticostriatal Synapse by Acting at CaV2.1 (P/Q-Type) Calcium Channels and GIRK (KIR3) …
H Vázquez-Vázquez, C Gonzalez-Sandoval… - Cellular and Molecular …, 2022 - Springer
Histamine H3 Receptor Activation Modulates Glutamate … IR 3 channels has been shown
in Xenopus oocytes upon the … of the GIRK channels present in the corticostriatal terminals. …
in Xenopus oocytes upon the … of the GIRK channels present in the corticostriatal terminals. …
Opposite Functions of Histamine H1 and H2 Receptors and H3 Receptor in Substantia Nigra Pars Reticulata
FW Zhou, JJ Xu, Y Zhao… - Journal of …, 2006 - journals.physiology.org
… In Parkinson’s disease, histamine innervation and histamine H 3 receptor expression in
SNr … the function of different histamine receptors in SNr. Histamine increased SNr inhibitory …
SNr … the function of different histamine receptors in SNr. Histamine increased SNr inhibitory …
Histamine H3 receptors and their role in basal ganglia physiology and pathophysiology
JA Arias‐Montaño - Signal Transduction, 2007 - Wiley Online Library
… nervous system, which contains the great majority of histamine H3 receptors (H3Rs). These
… (2007) The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes. …
… (2007) The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes. …
Characterization of GAR‐2, a Novel G Protein‐Linked Acetylcholine Receptor from Caenorhabditis elegans
… We show that like GAR-1, GAR-2 couples to activation of the … by using the human histamine
H3 receptor as an outgroup. … injecting their cRNAs into Xenopus oocytes. Replacement of …
H3 receptor as an outgroup. … injecting their cRNAs into Xenopus oocytes. Replacement of …
Voltage‐dependence of the human dopamine D2 receptor
K Sahlholm, J Nilsson, D Marcellino, K Fuxe… - Synapse, 2008 - Wiley Online Library
… -coupled receptors also applies to the dopamine D2 receptor. … GIRK channel current
responses in Xenopus oocytes, we … The human histamine H3 receptor couples to GIRK channels …
responses in Xenopus oocytes, we … The human histamine H3 receptor couples to GIRK channels …
[HTML][HTML] Ligand-directed biased agonism at human histamine H3 receptor isoforms across Gαi/o-and β-arrestin2-mediated pathways
SN Rahman, F Imhaouran, R Leurs… - Biochemical …, 2023 - Elsevier
… The human histamine H 3 receptor (hH 3 R) is a neurotransmitter receptor in the central
nervous system (CNS) [1] that has been a longstanding drug target for various CNS disorders, …
nervous system (CNS) [1] that has been a longstanding drug target for various CNS disorders, …