Regulation of the Nitric Oxide Reduction Operon (norRVW) in Escherichia coli: ROLE OF NorR AND ς54 IN THE NITRIC OXIDE STRESS RESPONSE

AM Gardner, CR Gessner, PR Gardner - Journal of Biological Chemistry, 2003 - ASBMB
… Neither NorR nor ς 54 was essential for NO-mediated induction of the NO dioxygenase (flavohemoglobin)
encoded byhmp. However, elevated NOR activity inhibited NO dioxygenase

Nitric oxide and nitrosative stress tolerance in bacteria

RK Poole - Biochemical Society Transactions, 2005 - portlandpress.com
flavohaemoglobin (Hmp). Aerobically, Hmp detoxifies NO by acting as an NO denitrosylase
or ‘oxygenase’ … The flavohaemoglobin-encoding gene of Escherichia coli, hmp, responds to …

Regulation of the flavorubredoxin nitric oxide reductase gene in Escherichia coli: nitrate repression, nitrite induction, and possible post-transcription control

PN da Costa, M Teixeira… - FEMS microbiology …, 2003 - academic.oup.com
… NO reductase activity, flavohemoglobin and the pentaheme … (Hmp), which has a much
higher activity as NO dioxygenase … prior to its introduction into water. When cultures, grown …

The X-ray Structure of Ferric Escherichia coliFlavohemoglobin Reveals an Unexpected Geometry of the Distal Heme Pocket

A Ilari, A Bonamore, A Farina, KA Johnson… - Journal of Biological …, 2002 - ASBMB
… lipid-free Escherichia coli flavohemoglobin has been solved to … -oxide dioxygenase activity
stands as the major functional … The final model includes all 396 residues and 180 water

Cloning and characterization of two flavohemoglobins from Aspergillus oryzae

S Zhou, S Fushinobu, Y Nakanishi, SW Kim… - Biochemical and …, 2009 - Elsevier
… Enterobacteria such as Escherichia coli should frequently … into a Waters Model 600E HPLC
System (Waters) equipped with a … Essential residues for heme binding and NO dioxygenase

A combination of cytochrome c nitrite reductase (NrfA) and flavorubredoxin (NorV) protects Salmonella enterica serovar Typhimurium against killing by NO in anoxic …

PC Mills, G Rowley, S Spiro, JCD Hinton… - …, 2008 - microbiologyresearch.org
flavohaemoglobin (HmpA) enzyme has a well characterized NO dioxygenase activity in
both Escherichia coli (… detoxifies nitric oxide in aerobic, but not anaerobic, Escherichia coli. …

Nitric Oxide in Chemostat-Cultured Escherichia coli Is Sensed by Fnr and Other Global Regulators: Unaltered Methionine Biosynthesis Indicates Lack of S Nitrosation

ST Pullan, MD Gidley, RA Jones, J Barrett… - Journal of …, 2007 - Am Soc Microbiol
… dependent denitrosylase (“dioxygenase”) reaction converting … for 16 to 24 h in a shaking
water bath at 42C. The slides were … mutation of the flavohemoglobin Hmp decreases survival of …

Flavohemoglobin and nitric oxide detoxification in the human protozoan parasite Giardia intestinalis

D Mastronicola, F Testa, E Forte, E Bordi… - Biochemical and …, 2010 - Elsevier
… NO-equilibrated water was … flavoHb plays in Giardia a defense role and contributes to
enhance the parasite resistance to NO-stress. Nonetheless, the NO-induced expression of flavoHb

The flavohemoglobin BCFHG1 is the main NO detoxification system and confers protection against nitrosative conditions but is not a virulence factor in the fungal …

JL Turrion-Gomez, AP Eslava, EP Benito - Fungal Genetics and Biology, 2010 - Elsevier
… of this NO dioxygenase activity with a flavohemoglobin has … cinerea flavohemoglobin likely
does not play a significant role … that the flavohemoglobin is the main NO detoxification system …

Inducible Defense Mechanism against Nitric Oxide in Candida albicans

BD Ullmann, H Myers, W Chiranand, AL Lazzell… - Eukaryotic …, 2004 - Am Soc Microbiol
… in groups in bioclean hoods and provided with water and food ad libitum. Eight mice …
Escherichia coli nitric-oxide dioxygenase (flavohemoglobin). The B10 tyrosine hydroxyl is essential