NsrR: a key regulator circumventing Salmonella enterica serovar Typhimurium oxidative and nitrosative stress in vitro and in IFN-γ-stimulated J774. 2 macrophages

NJ Gilberthorpe, ME Lee, TM Stevanin… - …, 2007 - microbiologyresearch.org
flavohaemoglobin Hmp has emerged as the most significant … of NO in Escherichia coli and
Salmonella, but the roles of other … The results indicate the critical role of Hmp in protection of …

Crystal structure of the flavohemoglobin from Alcaligenes eutrophus at 1.75 A resolution.

U Ermler, RA Siddiqui, R Cramm, B Friedrich - The EMBO journal, 1995 - embopress.org
The molecular structure of the flavohemoglobin from Alcaligenes eutrophus has been
determined to a resolution of 1.75 A and refined to an R‐factor of 19.6%. The protein comprises …

Oxidative stress modulates the nitric oxide defense promoted by Escherichia coli flavorubredoxin

JM Baptista, MC Justino, AMP Melo… - Journal of …, 2012 - Am Soc Microbiol
… Hmp acts as an NO dioxygenase or reductase, but the latter activity is low (11, 14). In contrast,
Flavohemoglobin detoxifies nitric oxide in aerobic, but not anaerobic, Escherichia coli. …

Nitric oxide-mediated induction of dispersal in Pseudomonas aeruginosa biofilms is inhibited by flavohemoglobin production and is enhanced by imidazole

X Zhu, HS Oh, YCB Ng, PYP Tang… - Antimicrobial agents …, 2018 - Am Soc Microbiol
… the NO dioxygenase activity of flavohemoglobin, attenuated … is capable of sensing NO in
Escherichia coli (39). The NO-… prepared in Milli-Q water at different concentrations. Biofilms …

Distinct nitrite and nitric oxide physiologies in Escherichia coli and Shewanella oneidensis

Q Meng, J Yin, M Jin, H Gao - Applied and Environmental …, 2018 - Am Soc Microbiol
… decompose NO include flavohemoglobin (Hmp) functioning as nitric-oxide dioxygenase (NOD), …
(such as flavin reductase Fre of Escherichia coli), and the hybrid cluster protein (Hcp) (13…

Trichomonas vaginalis degrades nitric oxide and expresses a flavorubredoxin-like protein: a new pathogenic mechanism?

P Sarti, PL Fiori, E Forte, P Rappelli, M Teixeira… - Cellular and Molecular …, 2004 - Springer
… sistent with those of the Escherichia coli A-type flavoprotein (… be also metabolized aerobically
by flavohaemoglobin [11, 12]… NO-dioxygenases [12], although the in vivo significance of this …

[HTML][HTML] A critical role for staphylococcal nitric oxide synthase in controlling flavohemoglobin toxicity

RM Singh, SS Chaudhari, S Panda, EH Hutfless… - Redox Biology, 2023 - Elsevier
… Under these conditions, growth can only resume once nitric oxide (NO) is detoxified by the
flavohemoglobin Hmp. Paradoxically, S. epidermidis produces endogenous NO through its …

Flavin-containing heme enzymes

CG Mowat, B Gazur, LP Campbell… - Archives of Biochemistry …, 2010 - Elsevier
… dehydrogenase, flavohemoglobin, which has nitric oxide dioxygenase activity, and …
Escherichia coli of nitric oxide inducible NAD(P)H, O 2 and FAD-dependent nitric oxide dioxygenase

Nonsymbiotic hemoglobins and stress tolerance in plants

C Dordas - Plant Science, 2009 - Elsevier
… plants act as part of a soluble, terminal, NO dioxygenase system, … The flavohemoglobins
that are used to detoxify NO in … The expression of Escherichia coli flavohemoglobin, which …

Resonance Raman studies on the flavohemoglobin of the protist Giardia intestinalis: evidence of a type I/II-peroxidase-like heme environment and roles of the active …

B Lukaszewicz, E McColl, J Yee, S Rafferty… - JBIC Journal of …, 2017 - Springer
… ], likely through water molecules [9], and two residues on helix E (… distal residue to the heme
iron in the flavohemoglobin of E. … it is relevant for the NO-dioxygenase reaction and it was not …