[HTML][HTML] Deletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse …
… (especially lipid metabolism, redox status, and immune … significantly impaired in TgAPP
mice compared to WT mice (… the hippocampus and the parietal cortex of TgAPP mice and …
mice compared to WT mice (… the hippocampus and the parietal cortex of TgAPP mice and …
Amyloid beta receptors responsible for neurotoxicity and cellular defects in Alzheimer's disease
… , insoluble amyloid prepared from AD brains fails to impair … vitro and in the cell membrane
of the AD brains and mice [17–… in 4-month-old 3xTg-AD mice which have no detectable Aβ …
of the AD brains and mice [17–… in 4-month-old 3xTg-AD mice which have no detectable Aβ …
… fatty acids reduce brain lipid peroxidation and hippocampal amyloid β-peptide levels, without discernable behavioral effects in an APP/PS1 mutant transgenic mouse …
… immunoreactivity in the cerebral cortex and hippocampus of a wild-type mouse (A), an AD
… contribute to cognitive impairment in APP/PS1 double mutant transgenic mice used in the …
… contribute to cognitive impairment in APP/PS1 double mutant transgenic mice used in the …
Accumulated amyloid-β peptide and hyperphosphorylated tau protein: relationship and links in Alzheimer's disease
HC Huang, ZF Jiang - Journal of Alzheimer's disease, 2009 - content.iospress.com
… and dephosphorylation is disturbed in neurons. Accumulated … and 4 months in the neocortex
of 3xTg-AD mice, while the Aβ … fibrillar forms of Aβ to plasma membrane proteins has been …
of 3xTg-AD mice, while the Aβ … fibrillar forms of Aβ to plasma membrane proteins has been …
Glutathione Peroxidase-1 Knockout Facilitates Memory Impairment Induced by β-Amyloid (1–42) in Mice via Inhibition of PKC βII-Mediated ERK Signaling; Application …
EJ Shin, YH Chung, N Sharma, BT Nguyen… - Neurochemical …, 2020 - Springer
… cerebral cortex and hippocampus of rat model of AD [6, 7]. Selenomethionine has been shown
to reduce cognitive impairments in the triple transgenic mouse … the cell membrane, the Aβ …
to reduce cognitive impairments in the triple transgenic mouse … the cell membrane, the Aβ …
[HTML][HTML] Convergence of amyloid-β and tau pathologies on mitochondria in vivo
… when cortical brain cells of P301L tau transgenic pR5 mice … Similarly, cognitive impairment
manifested in 3xTg-AD mice … in another triple transgenic mouse model 3xTg-AD (P301Ltau/…
manifested in 3xTg-AD mice … in another triple transgenic mouse model 3xTg-AD (P301Ltau/…
Β-amyloid and oxidative stress: Perspectives in drug development
G Caruso, SF Spampinato, V Cardaci… - Current …, 2019 - ingentaconnect.com
… APP and its proteolytic enzymes reach the cell membrane, where … in 3xTg-AD mice promotes
a strong reduction in hippocampal … Amyloid β-peptide (142)-induced oxidative stress in …
a strong reduction in hippocampal … Amyloid β-peptide (142)-induced oxidative stress in …
Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease
M Perluigi, F Di Domenico… - Physiological …, 2024 - journals.physiology.org
… the abnormal deposition of amyloid β-peptide (Aβ) … redox proteomics analyses have
identified a significant number of HNE-modified brain proteins in AD and mild cognitive impairment …
identified a significant number of HNE-modified brain proteins in AD and mild cognitive impairment …
Amyloid beta-related alterations to glutamate signaling dynamics during Alzheimer's disease progression
… Neuronal cell cultures taken from the cortex and hippocampus of Tg2576 transgenic AD mice
… In 3xTg-AD mice, GS+ astrocyte distribution mirrored that of GFAP+ distribution in the DG …
… In 3xTg-AD mice, GS+ astrocyte distribution mirrored that of GFAP+ distribution in the DG …
Why is the amyloid beta peptide of Alzheimer's disease neurotoxic?
A Rauk - Dalton Transactions, 2008 - pubs.rsc.org
… of a small peptide, the amyloid β-peptide (Aβ), which is the … in neuronal and endothelial
cell membrane permeability. Recent … α-secretase in the 3xTg-AD murine model of Alzheimer …
cell membrane permeability. Recent … α-secretase in the 3xTg-AD murine model of Alzheimer …