… or the cerebral cortex … impaired (MCI) and AD brain tissues. Furthermore, genetic ablation
of NOX prevented the oxidative stress and cerebrovascular dysfunction in transgenic mice. …

… and redox homeostasis was … mouse model of AD (3xTgAD), it has been shown that
orchiectomized males presented with increased Aβ accumulation in the brain, coupled with impaired …

… From a neuropathological point of view, amyloid-β-peptide (Aβ) … glucose transporter at the
plasma membrane) and metabolism … comparison 3xTg-AD mice with sucrose-treated WT mice …

… plaques that are mainly composed of amyloid-β peptide (Aβ). … A subsequent cleavage of
C83 within the plasma membrane … potential, ROS production and ATP levels) is partly impaired …

… Cerebral oxidative stress, mitochondrial impairment, synaptic … -STZ delivery produces brain
cerebral glucose deregulation … system [67], the levels of GSH/GSSG and the redox states of …

… H 2 O 2 that leaks through plasma membranes to the extracellular … increased production of
ROS and impairment of anti-oxidant … homeostasis in presymptomatic 3xTg-AD miceJ Neurosci…

… SK2 channels is increased in a 3xTg AD mouse model [46], … mild cognitive impairment have
demonstrated hippocampal … the activity of the plasma membrane NCLX, whose expression …

… Thus, hippocampal NO production could be another marker for the impairment of synaptic
plasticity in amyloidosis-… , tau pathology, and, ultimately, memory loss in 3XTg-AD mice, [89]. …

… An important underpinning of glutamate-dependent dysregulation of synaptic plasticity and
behavioral impairment in this study is by the alteration to cholinergic neurotransmitter system, …

… and redox changes in mature primary rat hippocampal neurons. … hippocampus and cortex of
a 3-month-old 3xTg-AD mouse … the hippocampus of a 15-month-old 3xTg-AD mouse female […