… (38) of the TCR have been solved, and the Vα domain shows … binding sites for bacterial
superantigens on soluble class II … for stable binding to class II major histocompatibility complex …

… , conventionally through the variable β-domain of TCR (TCRVβ). They … bind major
histocompatibility complex (MHC) class II … interfaces between SEH and TCR in solution using …

… binding of the SAg to both a T cell receptor (TCR) on a T cell and a class II product of the
major histocompatibility complex (… This cross-linking leads to aggregation of the TCR complex …

… superantigens share a core major histocompatibility complex (MHC) class II binding site, …
An acidic, solvent-exposed loop of the MHC class I molecule, homologous to the region that …

… in solution and consequently may crosslink MHC class II molecules (… its N-terminal domain
on the MHC class II molecule. This … Cross-linking of major histocompatibility complex class II …

… , superantigens bind to major histocompatibility complex (… showed the formation of (SEA)2–DR1
trimers in solution [ … regions 1 and 2 (CDR1 and CDR2) and hypervariable region 4 (HV4…

… Major histocompatibility complex (MHC) class II molecules play an important role in antigen
presentation, with the binding … In this process, the invariant chain (Ii) acts as a chaperone for …

… The structure of the peptide binding domain of class II major … cases class II proteins were
cocrystallized with superantigens… to class I major histocompatibility complex molecule binding. ] …

… domain of the TCR. SAGs bind their Vß bind simultaneously to major histocompatibility com-
… times with mother liquor and transferred to a cryoprotectant solution in SAG-TCR complexes …

… for binding the α subunit of major histocompatibility complex … , major structural deviations
occur in domain II, in region 198–… pH 7.8 and 4 μL protein stock solution of 2 mg/mL) suspended …