Structure studies of the human class II major histocompatibility complex protein HLA-DR1

Z Zavala-Ruiz - 2004 - dspace.mit.edu
region of the peptide binding site of the human class II majorsolution mixed with luL of 11
mg/mL protein complex. For x-… Superantigen was clear and continuous except for HLA-DRl […

The structural basis of T cell activation by superantigens

H Li, A Llera, EL Malchiodi… - Annual review of …, 1999 - annualreviews.org
… the Vβ domain of the T cell receptor (TCR) and with major … of peptides bound to major
histocompatibility complex (MHC) … the demonstration that SEA 2 -DR1 trimers exist in solution (130)…

[HTML][HTML] Structure of staphylococcal enterotoxin E in complex with TCR defines the role of TCR loop positioning in superantigen recognition

KEJ Rödström, P Regenthal, K Lindkvist-Petersson - Plos one, 2015 - journals.plos.org
… and the major histocompatibility complex (MHC) class II and … with an extracellular
antigen-binding domain, consisting of an … In solution, flexibility in this region could allow for a more …

[PDF][PDF] The characterization of major histocompatibility complex class II signal transduction pathways in antigen presenting cells

R Haylett - 2009 - publications.rwth-aachen.de
… other domains serving as the peptidebinding cleft, … major histocompatibility complex
class II molecules by conventional means. Superantigens bind outside the MHC-II peptide-binding

Toxic shock syndrome and bacterial superantigens: an update

JK McCormick, JM Yarwood… - Annual Reviews in …, 2001 - annualreviews.org
… by binding to class II major histocompatibility complex … Both the Group I and II SAGs lack
the zinc-binding domain (… SPE C exists as a monomer in solution (91) and SPE C dimerization …

Zinc regulates cytokine induction by superantigens and lipopolysaccharide.

C Driessen, K Hirv, H Kirchner, L Rink - Immunology, 1995 - ncbi.nlm.nih.gov
… their major histocompatibility complex (MHC) class II-binding … after both LPS and superantigen
challenge within a clinically … domain of class II MHC molecules whereas TSST-1 binds to …

Display of ovalbumin peptides by murine Class II major histocompatibility complexes and the engineering of responding T cell receptors

BM Roy - 2012 - conservancy.umn.edu
During an induced immune response, the BALB/c strain of laboratory mouse presents ovalbumin
peptides by major histocompatibility complexes that stimulate responding T cells. This …

[HTML][HTML] Model for the peptide-free conformation of class II MHC proteins

CA Painter, A Cruz, GE López, LJ Stern… - PLoS One, 2008 - journals.plos.org
Class II major histocompatibility complex (MHC) are … within the binding groove of the MHC
II binding domain. Residues … binding of these conformationally-specific superantigen and …

Dual roles for class II major histocompatibility complex molecules in staphylococcal enterotoxin-induced cytokine production and in vivo toxicity

D Grossman, JG Lamphear, JA Mollick… - Infection and …, 1992 - Am Soc Microbiol
superantigens (47) has provided us with new insights into possible mechanisms of pathogenesis.
The SE and TSST specifically bind classII major histocompatibility complex (… the region

Insight into the structure and function of empty class II major histocompatibility complexes

GJ Carven - 2002 - dspace.mit.edu
… In class II MHC proteins, the lower domains are docked onto the peptide binding domain
coated gold chip, and monitored binding for the MEM antibodies in PBS solution. Endpoint …