Transient cervical nerve root compression in the rat induces bilateral forepaw allodynia and spinal glial activation: mechanical factors in painful neck injuries

RD Hubbard, BA Winkelstein - Spine, 2005 - journals.lww.com
… nociceptive responses for painful injuries in the neck. Therefore, this study investigates
whether transient cervical nerve root compression can produce pain in the rat and examines the …

Transient cervical nerve root compression modulates pain: load thresholds for allodynia and sustained changes in spinal neuropeptide expression

RD Hubbard, Z Chen, BA Winkelstein - Journal of biomechanics, 2008 - Elsevier
transient loading in a rat model of painful cervical nerve root … All rats were evaluated for
bilateral forepaw mechanical … Axonal damage assessment in the compressed nerve root and …

The roles of mechanical compression and chemical irritation in regulating spinal neuronal signaling in painful cervical nerve root injury

S Zhang, KJ Nicholson, JR Smith, TM Gilliland, PP Syré… - 2013 - sae.org
Transient compressive trauma to the nerve root that is held for … shown to cause transient
mechanical allodynia that lasted for … applied to induce cervical nerve root injuries in a rat model. …

Spinal Neuropeptide Responses in Persistent and Transient Pain Following Cervical Nerve Root Injury:(Presented at the 2004 CSRS Meeting)

SM Rothman, RA Kreider, BA Winkelstein - Spine, 2005 - journals.lww.com
… produce different mechanical allodynia patterns in the rat. … as painful models inducing persistent
and transient allodynia, … hind paw allodynia in lumbar models of low back pain 3–5,10,11…

An in vivo model of transient cervical nerve root compression: Thresholds for mechanical allodynia and neuronal responses

RD Hubbard - 2008 - search.proquest.com
… in the DRG, glial cell line-derived neurotrophic factor (GDNF) … and colleagues ligated the
lumbar nerve roots of rats with silk … to induce persistent bilateral mechanical allodynia and that …

Transient nerve root compression load and duration differentially mediate behavioral sensitivity and associated spinal astrocyte activation and mGLuR5 expression

KJ Nicholson, BB Guarino, BA Winkelstein - Neuroscience, 2012 - Elsevier
… A model of a transient nerve root compression in the rat has … study, both mechanical allodynia
and astrocyte activation were … spinal astrocyte activation is induced by compression of the …

Chemical and mechanical nerve root insults induce differential behavioral sensitivity and glial activation that are enhanced in combination

SM Rothman, BA Winkelstein - Brain research, 2007 - Elsevier
Rats underwent separate procedures: cervical nerve roottransient mechanics in mediating
behavioral sensitivity from … can induce mechanical allodynia and spinal glial activation and …

[图书][B] … role of mechanical signals during nerve root compression in the development of sustained pain and neurophysiological correlates that develop in the injured …

KJ Nicholson - 2013 - search.proquest.com
… a rat model of a transient cervical nerve root compression to … , that induce chronic pain after
transient nerve root compressionmechanical allodynia and thermal hyperalgesia following …

Time-dependent mechanics and measures of glial activation and behavioral sensitivity in a rodent model of radiculopathy

SM Rothman, KJ Nicholson… - Journal of Neurotrauma, 2010 - liebertpub.com
Transient cervical nerve root compression in the rat induces bilateral forepaw allodynia and
spinal glial activation: mechanical factors in painful neck injuriesSpine3019241932. Hubbard…

Sustained neuronal hyperexcitability is evident in the thalamus after a transient cervical radicular injury

PP Syré, CL Weisshaar, BA Winkelstein - Spine, 2014 - journals.lww.com
… in a rat model, with assessment of mechanical allodynia until … applied for 15 minutes that
induces pain, axonal … that glia are also activated at both the early onset of pain development 37 …