Trehalose6phosphatemediated phenotypic change in Acinetobacter baumannii

JJ Hubloher, S Zeidler, P Lamosa… - Environmental …, 2020 - Wiley Online Library
trehalose is synthesized in Acinetobacter baumannii from UPD-glucose and glucose-6-… at
high salinities indicating that trehalose is the cause of these phenotypes. We have questioned …

[引用][C] Trehalose-6-phosphate-mediated phenotypic change

JJ Hubloher, S Zeidler, P Lamosa, H Santos, B Averhoff… - 2020

Trehalose-deficient Acinetobacter baumannii exhibits reduced virulence by losing capsular polysaccharide and altering membrane integrity

CS Crippen, J Glushka, E Vinogradov… - …, 2021 - academic.oup.com
Acinetobacter baumannii has become a leading cause of bacterial nosocomial infections,
in … We became interested in examining the importance of trehalose in A. baumannii after …

Light modulates metabolic pathways and other novel physiological traits in the human pathogen Acinetobacter baumannii

GL Müller, M Tuttobene, M Altilio… - Journal of …, 2017 - Am Soc Microbiol
… work to the level of phenotype. Many of these traits show that light modulates metabolic
pathways, such as the PAA catabolic pathway, trehalose biosynthesis, and acetoin degradation, …

Characterization of the Acinetobacter baumannii growth phase-dependent and serum responsive transcriptomes

AC Jacobs, K Sayood, SB Olmsted… - FEMS Immunology & …, 2012 - academic.oup.com
Trehalose is a nonreducing disaccharide that is generated … baumannii trehalose production
contributes to the organism's … to what additional biological systems mediate the ability of A. …

Coping with low water activities and osmotic stress in Acinetobacter baumannii: significance, current status and perspectives

S Zeidler, V Müller - Environmental microbiology, 2019 - Wiley Online Library
baumannii, and remarkably, an MDR-phenotype increases survival of clinical, but significantly
… is the sugar trehalose, synthesized by OtsA (trehalose-6-phosphate synthase) and OtsB (…

K+ homeostasis is important for survival of Acinetobacter baumannii ATCC 19606 in the nosocomial environment

P König, B Averhoff, V Müller - International Microbiology, 2024 - Springer
Acinetobacter baumannii is very well adapted to both the human host and the hospital
environment. The latter is facilitated by multifactorial mechanisms including its outstanding ability …

[图书][B] The Respective Roles of BfmRs and PmrA in Stress Responses and Antibiotic Resistance in Acinetobacter baumannii

S Palethorpe - 2021 - search.proquest.com
baumannii (31) and addition of exogenous trehalose to A. … phenotypic transition are vital to
aid our understanding of A. … for resistance to complement-mediated bactericidal activity (56). …

Trehalose 6phosphate phosphatases of Pseudomonas aeruginosa

…, RB Gasser, JS Kim, MJ Coster, A Hofmann - The FASEB …, 2018 - Wiley Online Library
… accumulation of the metabolite trehalose 6-phosphate (T6P) results in a lethal phenotype
solute with implications in pathobiology of Acinetobacter baumannii. Environ. Microbiol. …

Desiccation tolerance in Acinetobacter baumannii is mediated by the two-component response regulator BfmR

JM Farrow III, G Wells, EC Pesci - PloS one, 2018 - journals.plos.org
variation in drying-resistance phenotypes that we observed was not the result of a phase
changebaumannii produces trehalose, mannitol, and glutamate in response to increased …