HGF/c-Met overexpressions, but not met mutation, correlates with progression of non-small cell lung cancer

M Gumustekin, A Kargi, G Bulut, A Gozukizil… - Pathology & Oncology …, 2012 - Springer
… HGF/c-Met pathway and its association with invasion related markers and clinicopathologic
… have pointed out several molecular targets including the Hepatocyte Growth Factor (HGF)/c-…

[HTML][HTML] Cancer stem cells, EMT, and developmental pathway activation in pancreatic tumors

S Hindriksen, MF Bijlsma - Cancers, 2012 - mdpi.com
… migration and invasion of pancreatic cancer cells, whereas … hepatocyte growth factor (HGF)
in both pancreatic cancer … is increased as a result of hypoxia, possibly via regulation by …

[PDF][PDF] HGF/MET Axis Induces Tumor Secretion of Tenascin-C and Promotes Stromal Rewiring in Pancreatic Cancer. Cancers 2021, 13, 3519

C Modica, M Olivero, F Zuppini, M Milan, C Basilico… - 2021 - academia.edu
… as a pro-invasive factor on pancreatic cancer cells, little is known … The hypoxic environment
in tumor-stromal cells accelerates … the activation of paracrine hepatocyte growth factor/c-Met

… , a multitargeted kinase inhibitor, suppresses the progression of pancreatic cancer by disrupting the interaction between pancreatic cancer cells and stellate cells

K Inoue, H Ohtsuka, M Tachikawa, F Motoi, M Shijo… - Pancreas, 2017 - journals.lww.com
hepatocyte growth factor (HGF), promote PCC proliferation, invasion, and migration, partially
through … also suggested that the paracrine pathway was essential to the growth of PCCs, …

Impact of tumor microenvironment and epithelial phenotypes on metabolism in breast cancer

HA Brauer, L Makowski, KA Hoadley… - Clinical Cancer …, 2013 - AACR
… Cytokine arrays identified hepatocyte growth factor (HGF) as … invasive cancers exhibiting
increased aerobic glycolysis (3) … may be regulated by tumorstromal interactions. GLUT1–4 are …

Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1α in non-small cell lung cancer cells

L Xu, MB Nilsson, P Saintigny, T Cascone, MH Herynk… - Oncogene, 2010 - nature.com
Tumor-stromal cell interaction under hypoxia increases the invasiveness of pancreatic
cancer cells through the hepatocyte growth factor/c-Met pathway. Int J …

[HTML][HTML] Prognostic impact of a compartment-specific angiogenic marker profile in patients with pancreatic cancer

C Kahlert, M Fiala, G Musso, N Halama, S Keim… - Oncotarget, 2014 - ncbi.nlm.nih.gov
… been proposed as relevant non-invasive surrogate markers in tumor disease [… that poor
pericyte coverage increases hypoxic strain in breast cancer, which … HGF hepatocyte growth factor …

[HTML][HTML] Signaling pathways mediating epithelial-mesenchymal crosstalk in pancreatic cancer: Hedgehog, Notch and TGFβ

JM Bailey, SD Leach - 2012 - europepmc.org
… endothelial growth factor (VEGF), hepatocyte growth factor (… increases the relevance of
this pathway for tumor-stromal … ducts of the pancreas and also in invasive pancreatic cancer. …

The clinical value of serum hepatocyte growth factor levels in patients undergoing primary radiotherapy for glioma: effect on progression-free survival

Q Liang, Z Mo, P Wang, X Li, Z Liu, Z Zhou - Medical oncology, 2014 - Springer
… gliomas is their striking neovascularisation, proliferation and invasion. These are generally
… with increased IMD, but HGF gene expression is upregulated by hypoxia under experimental …

Upregulation of HGF and c-MET is associated with subclinical central lymph node metastasis in papillary thyroid microcarcinoma

BS Koo, JM Kim, ST Seo, YH Yoon, KR Kwon… - Annals of surgical …, 2014 - Springer
… Among them, hepatocyte growth factor (HGF) affects … human cancers, including breast cancer,
pancreatic cancer, renal … increased invasion and migration of PTC cells due to HGF/c-Met …