… PHO4 gene would exhibit impaired Aph1 secretion during … similar to the WT at elevated
temperature and produces WT-like … Purvalanol A treatment uncoupled PHO signaling from …

… affects mRNA synthesis, whereas the other affects mRNA … thal temperature (33 C) and
determined the steady-state mRNA … distinct functions that can be uncoupled by specific mutations. …

… UPR pathway was elucidated is Cryptococcus neoformans. … domain was shown to be
impaired in eIF2α phosphorylation in … /SEC63 it was possible to uncouple the ER stress from the …

… the human fungal pathogen Cryptococcus neoformans. mBio 2019, … Uncoupling of mRNA
synthesis and degradation impairs adaptation to host temperature in Cryptococcus neoformans…

… host, two phenotypes largely determine a successful infection: growth at host physiological
temperature (37C) … a transcript degradation site, SGs are believed to regulate mRNA storage, …

… Cryptococcus neoformans: data were obtained for variety … temperature, impairing its ability
to grow at the physiological … Another example of a microorganism exhibiting adaptability in …

… albicans and Cryptococcus neoformans were shown to stimulate a … to high temperatures
and oxidative stress (154). … In fact, the zwf1 idp2 double mutant is impaired for growth in media …

… pathogen must adapt to the challenges of its host environment. … that Inz-1 is fully degraded
after an incubation of 1 hr at … Reaction plates were incubated at room temperature for 10 min …

… , is generally associated with impaired fitness and developmental … , extreme temperatures
and those mimicking wild or host … , while increased ERG11 mRNA expression was observed in …

… Candida albicans and Cryptococcus neoformans indicating … the molecular mechanisms of
hypoxia adaptation in A. fumigatus … Hypoxia affects transcript levels of enzymes involved in the …