[HTML][HTML] Soluble tumor necrosis factor-alpha-induced hyperexcitability contributes to retinal ganglion cell apoptosis by enhancing Nav1. 6 in experimental glaucoma

S Cheng, HN Wang, LJ Xu, F Li, Y Miao, B Lei… - Journal of …, 2021 - Springer
… 5% CO 2 ) artificial cerebral spinal fluid (ACSF) containing the … To isolate RGCs, the retinas
of anesthetized rats were … primary antibodies were used: monoclonal mouse anti-β-actin (1:…

[HTML][HTML] Neuroinflammation in the anterior cingulate cortex: the potential supraspinal mechanism underlying the mirror-image pain following motor fiber injury

QY Li, SX Chen, JY Liu, PW Yao, YW Duan… - Journal of …, 2022 - Springer
tumor necrosis factor alpha (TNF-α) in contralateral ACC … the mechanical allodynia in the
hind paws of rats and mice [45]. … Interaction between spinal cord and ACC activity contributes to …

Peripheral and central sensitization in remote spinal cord regions contribute to central neuropathic pain after spinal cord injury

SM Carlton, J Du, HY Tan, O Nesic, GL Hargett… - Pain®, 2009 - Elsevier
… were made from spinal cord dorsal horn neurons in sham and 35 day SCI rats. Rats were …
Based on animal studies, nociceptors can contribute to mechanical allodynia with lowered …

P2Y12 and P2Y13 receptors involved in ADPβs induced the release of IL-1β, IL-6 and TNF-α from cultured dorsal horn microglia

PW Liu, MX Yue, R Zhou, J Niu, DJ Huang… - Journal of pain …, 2017 - Taylor & Francis
… Citation18 Up-regulation of TNF-α in mouse spinal cord contributes to vincristine-induced
mechanical allodynia. … -regulation of tumor necrosis factor-alpha in spinal cord contributes to …

Transforming growth factor-β1 impairs neuropathic pain through pleiotropic effects

S Echeverry, XQ Shi, A Haw, Z Zhang… - Molecular …, 2009 - journals.sagepub.com
… cells, TGF-β1 could contribute to restore homeostasis in a spinal cord with direct damage to
the … the spinal cord was not detected, one cannot exclude the possibility that up-regulation of …

[HTML][HTML] Intrathecal injection of spironolactone attenuates radicular pain by inhibition of spinal microglia activation in a rat model

Y Sun, L Peng, X Sun, J Bo, D Yang, Y Zheng, C Liu… - PloS one, 2012 - journals.plos.org
… Our previous experiment also revealed a notable up regulation of Iκβ-α in the … spinal cord.
The anti-inflammatory effect of spironolactone may underlie the main mechanisms contributing

Emerging targets in neuroinflammation-driven chronic pain

RR Ji, ZZ Xu, YJ Gao - Nature reviews Drug discovery, 2014 - nature.com
… 62 and astrocytes 63 in the spinal cord, which could contribute to increased production of …
mechanical allodynia and heat hyperalgesia that were induced by spinal nerve ligation in mice

MiR-30d Participates in Vincristine-Induced Neuropathic Pain by Down-Regulating GAD67

H Wang, Y Sun, Y Wu, YJ Shen, J Xia, YH Xu… - Neurochemical …, 2022 - Springer
… space of rats through the spinal cord segment space … The mechanical allodynia reached
its peak on day 5. Both of them … contribute to vincristine-induced hyperalgesia and allodynia. …

[HTML][HTML] The therapeutic potential of monocyte/macrophage manipulation in the treatment of chemotherapy-induced painful neuropathy

K Montague, M Malcangio - Frontiers in molecular neuroscience, 2017 - frontiersin.org
… Indeed, microglial communication with neurons in the spinal cord … and mechanisms underlying
vincristine-induced neuropathic pain… The contribution of such production to chemotherapy-…

Prevention of paclitaxel-induced neuropathy through activation of the central cannabinoid type 2 receptor system

M Naguib, JJ Xu, P Diaz, DL Brown… - Anesthesia & …, 2012 - journals.lww.com
… initiating signal 22 , 23 leads to activation of microglia, … 2 expression in the spinal cord of
paclitaxel-treated rats; and (… positive treatment effect indicates up-regulation with MDA7 and …