Procalcitonin and other biomarkers to improve assessment and antibiotic stewardship in infections-hope for hype?

P Schuetz, M Christ-Crain, B Müller - Swiss medical weekly, 2009 - smw.ch
… As plasma cortisol levels mirror the individual stress level … the prognostic value of cortisol
in patients with CAP [83]. … plasma levels of mature ET-1 are found during systemic infections

[HTML][HTML] Effect of a 14-day course of systemic corticosteroids on the hypothalamic-pituitary-adrenal-axis in patients with acute exacerbation of chronic obstructive …

P Schuetz, M Christ-Crain, U Schild, E Süess… - BMC pulmonary …, 2008 - Springer
… if left untreated upon acute stress (eg infection, acute exacerbation, trauma or … free cortisol
values or albumin or cortisol binding globulin concentrations to calculate free cortisol levels

Treatment of Cushing's syndrome: an endocrine society clinical practice guideline

…, JW Findling, MH Murad, J Newell-Price… - The Journal of …, 2015 - academic.oup.com
… recommend measuring serum cortisol or urine free cortisol (… and predisposes to severe,
systemic infection and/or sepsis … response, we advocate measuring serum cortisol levels as a …

[HTML][HTML] Changes in salivary biomarkers of stress, inflammation, redox status, and muscle damage due to Streptococcus suis infection in pigs

MJ López-Martínez, MAS Ornelas, RE Amarie… - BMC Veterinary …, 2023 - Springer
… there is an increase in the values of several salivary analytes … infectious diseases increase
cortisol, especially free cortisol [… in humans such as systemic lupus erythematosus, possibly …

Medication effects on salivary cortisol: Tactics and strategy to minimize impact in behavioral and developmental science

DA Granger, LC Hibel, CK Fortunato… - …, 2009 - Elsevier
… Without discounting the value and importance of the … is a drop in the free cortisol levels (ie,
lower salivary cortisol). … by the immune system during systemic infection. Medications that …

Beclomethasone diproprionate reduced airway inflammation without adrenal suppression in young children with cystic fibrosis: a pilot study

HA Wojtczak, GS Kerby, JS Wagener… - Pediatric …, 2001 - Wiley Online Library
… , adrenal function, and airway infection over a 2-month period… morning, we measured serum
cortisol levels every 2 hr using … counts to one third of baseline values, as we observed in this …

Plasma cortisol levels and reactivation of latent Epstein-Barr virus in response to examination stress

R Glaser, DK Pearl, JK Kiecolt-Glaser… - …, 1994 - Elsevier
… This study indicated that the normal theory p-values we report are … When 24-h urinefree
cortisol levels were evaluated on a … latently infected cells. We found that physiological doses of …

Biomarkers to improve diagnostic and prognostic accuracy in systemic infections

P Schuetz, M Christ-Crain, B Müller - Current opinion in critical …, 2007 - journals.lww.com
… of infections and guide antibiotic therapy. Promising prognostic biomarkers include cortisol,
… an earlier increase upon infection, a better negative predictive value, an increase despite …

[HTML][HTML] Association between high serum total cortisol concentrations and mortality from COVID-19

T Tan, B Khoo, EG Mills, M Phylactou… - The Lancet Diabetes & …, 2020 - thelancet.com
… Patients who were suspected to have SARS-CoV-2 infection had a … systemic glucocorticoid
treatment, or who had cortisol … of the cortisol assay at this high range, these values indicate …

Metabolic response to infection

WR Beisel - Annual review of medicine, 1975 - annualreviews.org
… that cortisol production is increased during acute infection, but rarely to values greater than
two to five times normal. … during morning hours in an uncomplicated systemic infection usually …