Metabolic cooperation in testis as a pharmacological target: from disease to contraception

MG Alves, TR Dias, BM Silva… - Current Molecular …, 2014 - ingentaconnect.com
… the passage of substances to the site where germ cells develop. … it can contribute to the
development of a male contraceptive. … action points in testis and vas deferens, will certainly be …

Differential inhibition in the human vas deferens by phenoxybenzamine: a possible mechanism for its contraceptive action

NIB Amobi, ICH Smith - Reproduction, 1995 - rep.bioscientifica.com
… These results suggest a mechanism for the male contraceptive action of phenoxybenzamine
by a selective blockade of longitudinal but not circular muscle contractions. The results are …

Muscarinic acetylcholine receptors: relevance to infertility and male contraception

CS Porto, TFG Lucas, ER Siu, C Royer… - … & Metabolic Agents …, 2008 - ingentaconnect.com
… -binding sites, mAChRs possess allosteric sites that bind … rat vas deferens [56-58], and M1
and M2 mAChRs are involved in the contraction of the epididymal region of rat vas deferens […

[引用][C] Biocompatibility of the vas deferens in relation to contraception

LK Kothari - Biocompatibility in clinical practice., 1982 - CRC Press Boca Raton.

[引用][C] The Challenge of Male Contraception

GMH Waites - Frontiers in Reproductive Physiology, 1992 - Wiley Eastern Limited

Phase I clinical trial of an injectable contraceptive for the male

SK Guha, G Singh, S Anand, S Ansari, S Kumar, V Koul - Contraception, 1993 - Elsevier
… Since the vas deferens is a site where interventions can be carried out … vas deferens and
the other is to alter the functional capabilities of the spermatozoa while it is in the vas deferens. …

Practice and development of male contraception: European Academy of Andrology and American Society of Andrology guidelines

…, S Honig, Z Kopa, K Lo, E Nieschlag, ST Page… - …, 2023 - Wiley Online Library
… dioxide, and calcium chloride) when injected into the vas deferens solidified into a
hydrogel inhibiting transit of spermatozoa through the vas. When fertility is desired, a non-invasive …

Update on novel hormonal and nonhormonal male contraceptive development

JE Long, MS Lee, DL Blithe - The Journal of Clinical …, 2021 - academic.oup.com
… is the potential for home assessment of sperm concentration … method to reversibly block the
vas deferens began in the 1970s in … Introduction of an effective reversible male contraceptive

[PDF][PDF] Studies on male fertility regulation in Indonesia

KM Arsyad - Medical Journal of Indonesia, 1995 - mji.ui.ac.id
INTRODUCTION … were among the first methods of male contraception. These methods are
usually … rat sperm and reduces the percentage of motile sperm from the vas deferens. This …

[PDF][PDF] Injectable Contraceptive for the Male

II Phase, V Deferens - academia.edu
… To meet these demands, contraceptive methods with the vas deferens as the site of
intervention were proposed and studied. These approaches included reversible valves,"* …