Metabolic cooperation in testis as a pharmacological target: from disease to contraception
… the passage of substances to the site where germ cells develop. … it can contribute to the
development of a male contraceptive. … action points in testis and vas deferens, will certainly be …
development of a male contraceptive. … action points in testis and vas deferens, will certainly be …
Differential inhibition in the human vas deferens by phenoxybenzamine: a possible mechanism for its contraceptive action
NIB Amobi, ICH Smith - Reproduction, 1995 - rep.bioscientifica.com
… These results suggest a mechanism for the male contraceptive action of phenoxybenzamine
by a selective blockade of longitudinal but not circular muscle contractions. The results are …
by a selective blockade of longitudinal but not circular muscle contractions. The results are …
Muscarinic acetylcholine receptors: relevance to infertility and male contraception
… -binding sites, mAChRs possess allosteric sites that bind … rat vas deferens [56-58], and M1
and M2 mAChRs are involved in the contraction of the epididymal region of rat vas deferens […
and M2 mAChRs are involved in the contraction of the epididymal region of rat vas deferens […
[引用][C] The Challenge of Male Contraception
GMH Waites - Frontiers in Reproductive Physiology, 1992 - Wiley Eastern Limited
Phase I clinical trial of an injectable contraceptive for the male
… Since the vas deferens is a site where interventions can be carried out … vas deferens and
the other is to alter the functional capabilities of the spermatozoa while it is in the vas deferens. …
the other is to alter the functional capabilities of the spermatozoa while it is in the vas deferens. …
Practice and development of male contraception: European Academy of Andrology and American Society of Andrology guidelines
…, S Honig, Z Kopa, K Lo, E Nieschlag, ST Page… - …, 2023 - Wiley Online Library
… dioxide, and calcium chloride) when injected into the vas deferens solidified into a
hydrogel inhibiting transit of spermatozoa through the vas. When fertility is desired, a non-invasive …
hydrogel inhibiting transit of spermatozoa through the vas. When fertility is desired, a non-invasive …
Update on novel hormonal and nonhormonal male contraceptive development
JE Long, MS Lee, DL Blithe - The Journal of Clinical …, 2021 - academic.oup.com
… is the potential for home assessment of sperm concentration … method to reversibly block the
vas deferens began in the 1970s in … Introduction of an effective reversible male contraceptive …
vas deferens began in the 1970s in … Introduction of an effective reversible male contraceptive …
[PDF][PDF] Studies on male fertility regulation in Indonesia
KM Arsyad - Medical Journal of Indonesia, 1995 - mji.ui.ac.id
… INTRODUCTION … were among the first methods of male contraception. These methods are
usually … rat sperm and reduces the percentage of motile sperm from the vas deferens. This …
usually … rat sperm and reduces the percentage of motile sperm from the vas deferens. This …
[PDF][PDF] Injectable Contraceptive for the Male
II Phase, V Deferens - academia.edu
… To meet these demands, contraceptive methods with the vas deferens as the site of
intervention were proposed and studied. These approaches included reversible valves,"* …
intervention were proposed and studied. These approaches included reversible valves,"* …