… of the pancreatic islets with the host’s systemic vasculature. In … driver of vascularization but
may also limit islet survival after … systems, but these typically need excess islets to achieve …

… for vascular endothelial growth factor VEGF-A in pancreatic … We conclude that VEGF-A is
required in pancreatic islets for normal … Thus, VEGF-A is a key factor for pancreatic islet function. …

… The pancreatic vascular endothelium secretes paracrine … -derived CTGF results in decreased
islet vascularity associated … find that CTGF produced by the β cells themselves is required …

… of the cells in the pancreatic islets. Dysfunction of these cells … to encourage the islet
vascularisation required for basement … contact with intra-islet vascular endothelial cells or …

… [106] but also may alter the morphology of pancreatic islets and … -A dose to potentiate islet
vascularization is subject to further … A dysfunctional intra-islet vascular endothelium may …

… -localized growth factors, such as vascular endothelial growth … The pancreatic islets of mice
and humans have two distinct … in adult β-cells for 2 weeks stimulated islet angiogenesis and …

… Pancreatic islets are discrete, spherical clusters of cells … endothelial growth factor A (VEGF-A),
which binds VEGF … -A expression not only reduces islet vascularity 10-fold but also leads …

… Vascular endothelial growth factor A (VEGF-A) has been … well as impaired islet vascularization
and endothelial fenestration.59-… that proper vasculature is required for lung development (…

… Native pancreatic islets are vascularised by a dense network … islet vascularisation and
islet growth in early development. … , but required for vascular endothelial growth factor-induced …

… vascular endothelial growth factor A … It is important to note that these transcription factors
can be involved at multiple levels of pancreatic development, ie during organogenesis, …