All-trans retinoic acid ameliorates glycemic control in diabetic mice via modulating pancreatic islet production of vascular endothelial growth factor-A

CY Chien, TA Yuan, CHH Cho, FP Chang… - Biochemical and …, 2016 - Elsevier
… Thus, there is an urgent need to develop strategies to improve the … Pancreatic islets are
highly vascularized and are known to express VEGF-A [22], [26]. Furthermore, the development

Donor islet endothelial cells in pancreatic islet revascularization

D Nyqvist, S Speier, R Rodriguez-Diaz, RD Molano… - Diabetes, 2011 - Am Diabetes Assoc
Pancreatic islets are interspersed by a dense and tortuous … by overexpression of vascular
endothelial growth factor-A (… rate of islet graft vascularization, it does not increase the vascular

Endothelial cells in endogenous and transplanted pancreatic islets: differences in the expression of angiogenic peptides and receptors

G Mattsson, A Danielsson, V Kriz, PO Carlsson… - Pancreatology, 2006 - karger.com
… receptors on islet endothelial cells (EC), we needed methods … angiogenesis activator
Vascular endothelial growth factor C … EC from all islet specimen investigated in this study; that is …

Vascular niche of pancreatic islets

J Olerud, Å Johansson, PO Carlsson - Expert review of …, 2009 - Taylor & Francis
… of the high islet vascularization in the adult, as well as the … the pancreas, close proximity
to blood vessel endothelium in … provided by islet endothelial cells seem not only important to …

Development of the human pancreas and its vasculature—an integrated review covering anatomical, embryological, histological, and molecular aspects

BM Henry, B Skinningsrud, K Saganiak… - Annals of Anatomy …, 2019 - Elsevier
Vascular endothelial growth factor A (VEGFA) is one of the … It was reported that the pancreatic
islets are primarily located … pancreas: (1) a large islet population that contains a dense …

VASCULAR ENDOTHELIAL GROWTH FACTOR IS INCREASED IN DEVASCULARIZED RAT ISLETS OF LANGERHANS IN VITRO1

DL Gorden, SJ Mandriota, R Montesano, L Orci… - …, 1997 - journals.lww.com
… Although the pattern of vascularization may vary with islet size, and from species to species,
angiogenesis in vivo, one of the most important of which is vascular endothelial growth

[HTML][HTML] The islet endothelial cell: a novel contributor to beta cell secretory dysfunction in diabetes

MF Hogan, RL Hull - Diabetologia, 2017 - Springer
… However, the islet also includes several important non-endocrine cell types, … exist in islet
vascularisation and morphology in human islets compared … Vascular endothelial growth factor …

Disruption of the pancreatic vasculature in zebrafish affects islet architecture and function

ST Mullapudi, GLM Boezio, A Rossi, M Marass… - …, 2019 - journals.biologists.com
… to circulating metabolites, pancreatic islets are crucial in regulating … To interrupt vascularization
of the islet, we expressed … cell behavior at single-cell resolution are needed to improve …

INGAP-PP effects on β-cell mass and function are related to its positive effect on islet angiogenesis and VEGFA production

CL Román, B Maiztegui, H Del Zotto… - Molecular and Cellular …, 2018 - Elsevier
… is necessary for correct pancreatic growth and development of … In this context we assume
that it could be important to test the … of pancreatic islets per area unit (p < 0.05; Fig. 1AC). Mean …

[HTML][HTML] Vascular development in the vertebrate pancreas

DB Azizoglu, DC Chong, A Villasenor… - Developmental …, 2016 - Elsevier
… basic vascular anatomy of the adult pancreas, as well as islet … and how the pancreatic
epithelium becomes vascularized, as … Cell type specific expression of vascular endothelial growth