… , we demonstrate that delivery of vascular endothelial growth … and permeability effects that
are essential to angiogenesis ( 19 … developing and mature islets ( 12–14, 20, 21 ), even though …

… by PCR before vascular endothelial cells are identifiable by … the developing lung and pancreas
at a time when vascular … the belief that they are important regulators of angiogenesis and …

… via upregulating vascular endothelial growth factor-A (VEGF-A… affects fetal islet development
and support an essential role of … Indeed, pancreatic islets are highly vascularized and VEGF-…

… PTP1B increased vascular endothelial growth factor A secretion … We demonstrate that grafts
of pancreatic islets lacking … in improved vascularization of PTP1B −/− tx balb-stz islet grafts. …

… beta-cells and endothelial cells in the pancreatic islets of … During early pancreatic development,
vascular endothelial … Therefore, islet vascularization appears to be a key element in the …

… are still needed to reverse type 1 diabetes in clinical islet … It also inhibits angiogenesis by
blocking the mobilization of pro-… -9 and mobilization of vascular endothelial growth factor. …

… Pancreatic islets were isolated to measure glucose-… In this context, vascular endothelial
growth factor-A (VEGF-A) … are significantly associated with islet angiogenesis and VEGF-A …

… were shown to be required for pancreas development and for … in islet and proximity of islets
with large pancreatic vessels. *… -expression of vascular endothelial growth factor A, or VEGF-A…

… The extensive vascular architecture of the islet is important for … through the secretion of
vascular endothelial growth factor (VEGF) … This might indicate that islet angiogenesis was blunted …

… Human pancreatic islets … Pancreatic islet production of vascular endothelial growth factor—a
is essential for islet vascularization, revascularization, and function. Diabetes 2006; 55: 2974…